Colts vs Cardinals Opening Odds, Betting Lines and Prediction for Week 16 Game on FanDuel Sportsbook

Week 15 NFL action has yet to wrap up, but FanDuel Sportsbook has already released NFL odds and lines for Week 16, giving us an early preview of next week's games.

Week 16's slate features a clash between the Indianapolis Colts and Arizona Cardinals.

Colts vs Cardinals Odds & Lines Week 16

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: IND: (+148) | ARI: (-176)
Spread: IND: +3.5 (-114) | ARI: -3.5 (-106)
Total: N/A — Over: (N/A) | Under: (N/A)

Colts vs Cardinals Prediction Week 16

Early NFL predictions and picks are from ESPN's Football Power Index (FPI).
Colts: 33.5% to win
Cardinals: 66.2% to win

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Isaiah De Los Santos is not a FanDuel employee. In addition to providing DFS gameplay advice, Isaiah De Los Santos also participates in DFS contests on FanDuel using his personal account, username zayyy05328. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.