NFL - Odds & Predictions

Colts vs Bills Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 11 Game

Devon Platana
Indianapolis Colts vs Buffalo Bills point spread, over/under, moneyline and betting trends for Week 11 NFL game.
Indianapolis Colts vs Buffalo Bills point spread, over/under, moneyline and betting trends for Week 11 NFL game. / Don Juan Moore/GettyImages
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Week 11's slate of games includes a showdown between the Indianapolis Colts and Buffalo Bills.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Colts vs Bills Point Spread

The Bills are 7-point home favorites against the Colts. Buffalo is -112 to cover the spread, while Indianapolis is -108 to cover as a 7-point underdog.

Colts vs Bills Over/Under

The over/under for the Colts vs Bills Week 11 NFL matchup is set at 49.5, with -110 odds on the over and -110 odds on the under.

Colts vs Bills Moneyline

The Colts vs Bills moneyline has Buffalo as a -320 favorite, while Indianapolis is a +260 underdog on the road.

Colts vs Bills Betting Trends

- Indianapolis is 5-2 against the spread (ATS) in its last seven games.
- Buffalo is 14-5-1 ATS in its last 20 games.
- The total has hit the under in seven of Indianapolis' last 10 games against Buffalo.
- The total has hit the under in six of Buffalo's last nine games as the favorite.

Colts vs Bills Prediction

All NFL predictions and picks are from numberFire's projection model.
Prediction: Buffalo Bills win (70.4%)

Colts vs Bills Odds

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: IND: (+260) | BUF: (-320)
Spread: IND: +7 (-108) | BUF: -7 (-112)
Total: 49.5 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: IND: (+100000) | BUF: (+4500)


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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