College Football Teams on Upset Alert in Week 10

The Pac-12 conference returns to action in college football this weekend with a loaded Week 10 slate featuring four top-25 matchups and two top-10 showdowns.

However, someone has to win, which always means someone has to lose, and here's a look at three favorites in danger of being upset in Week 10.

College Football Teams on Upset Alert This Week

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3. No. 23 Michigan (-2.5) vs No. 13 Indiana

This is a matchup between two Big Ten teams who have proven to be different contenders than believed to be from just one week ago. The Hoosiers shocked the Big Ten with a wild victory over Penn State in their first game, while a Michigan squad that blew the doors off Minnesota completely dropped the ball against a Michigan State opponent at home last Saturday. This one is a big question mark, but seeing the Wolverines as road favorites over a seemingly underestimated Hoosiers squad feels dicey.

2. No. 1 Clemson (-5.5) vs No. 4 Notre Dame

The elephant in the room here is Clemson's loss of star QB Trevor Lawrence for his team's biggest game of the year on the road against Notre Dame. Yet, the storyline that no one seems to be talking about from last Saturday's scare against Boston College is that backup QB D.J. Uiagalelei played very well in that start, going 30-for-41 with 342 yards, two TDs through the air and one on the ground with zero interceptions. In fact, it was really more on the Tigers' defense that allowed 28 points to BC in the first half. All that said, however, BC is not the same kind of opponent as Notre Dame, and asking a freshman QB to lead his team to victory over the No. 4 team in the country on the road in just his second start feels like a big ask if his defense isn't playing up to par.

1. No. 9 BYU (-2.5) vs No. 21 Boise State

Behind the talent of rising star QB and Heisman Trophy contender Zach Wilson the BYU Cougars have gotten off to an impressive 7-0 start. However, thanks to a postponed matchup with Army earlier this year, the toughest opponent they've faced to date is arguably a 4-2 Troy team, who the Cougars got at home no less. It's no secret that it's hard to win on that blue turf in Boise, and there's simply a lot of unknowns about both teams with Boise State having played just two games ahead of this Friday night matchup.

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David Hayes is not a FanDuel employee. In addition to providing DFS gameplay advice, David Hayes also participates in DFS contests on FanDuel using his personal account, username DavidWHayes. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.