Cardinals vs Browns Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 6 Game on FanDuel

Arizona Cardinals vs Cleveland Browns prediction, odds, spread, over/under and betting trends for NFL Week 6 game.
Arizona Cardinals vs Cleveland Browns prediction, odds, spread, over/under and betting trends for NFL Week 6 game. / Harry How/GettyImages
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Cardinals vs Browns Week 6 Game Info

NFL Regular Season — Week 6 Game
Arizona Cardinals (5-0, 3-0 Away) vs. Cleveland Browns (3-2, 2-0 Home)
Date: Sunday, October 17, 2021
Time: 4:05 p.m. EST
Venue: FirstEnergy Stadium — Cleveland, OH
Coverage: FOX

Cardinals vs Browns Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: ARI: (+138) | CLE: (-164)
Spread: ARI: +3 (-110) | CLE: -3 (-110)
Total: 48.5 — Over: (-105) | Under: (-115)
Public (Spread) Betting Percentages via oddsFire: ARI: (N/A) | CLE: (N/A)
Odds to Win Super Bowl LVI: ARI: (+1300) | CLE: (+1400)

Cardinals vs Browns Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: Cleveland Browns Win (58.5%)

Cardinals vs Browns Betting Trends

- Arizona is 4-1 against the spread (ATS) in its five games this season.
- The total has hit the under in eight of Arizona's last nine away games.
- Cleveland is 5-1 straight up in its last six home games.
- The total has hit the over in four of Cleveland's last six games against Arizona.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.