Buffalo vs Old Dominion Prediction, Odds, Spread, Date & Start Time for College Football Week 4 Game

Larry Rupp
Buffalo vs Old Dominion prediction, odds, spread, date & start time for college football Week 4 game.
Buffalo vs Old Dominion prediction, odds, spread, date & start time for college football Week 4 game. / Timothy T Ludwig/Getty Images
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Buffalo vs Old Dominion Week 4 Game Info

Week 4 College Football Game
Buffalo Bulls (1-2, 0-1 Away) vs. Old Dominion Monarchs (1-2, 1-0 Home)
Date: Saturday, September 25, 2021
Time: 6:00 p.m. EST
Venue: S.B. Ballard Stadium – Norfolk, VA
Coverage: ESPN+

Buffalo vs Old Dominion Spread & Odds

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: BUF: (-600) | ODU: (+420)
Spread: BUF: -13.5 (-108) | ODU: +13.5 (-112)
Total: 51.5 – Over: (-110) | Under: (-110)
Public (Spread) Betting Percentages via oddsFire: BUF: (N/A) | ODU: (N/A)

Buffalo vs Old Dominion Prediction & Pick

All NCAAF predictions & expert picks are according to numberFire.
Winning Percentage Prediction: Buffalo: (98.0%) | Old Dominion: (2.0%)

Buffalo vs Old Dominion Head-to-Head Record & Betting Trends

- This is the first all-time head-to-head matchup between Buffalo and Old Dominion.
- Buffalo is 14-4 against the spread (ATS) in its last 18 games.
- The total has hit the under in four of Buffalo's last five games.
- Old Dominion is 1-13 straight up in its last 14 games.
- The total has hit the over in four of Old Dominion's last six games.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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