Bills Projected by ESPN to Face Familiar Foe in Playoffs After Week 16
By Larry Rupp

The Buffalo Bills were able to salvage a season split against the New England Patriots with a win. Don't look now, but the possibility of a playoff matchup between these AFC East enemies is only growing stronger.
Ready for round three?
— Alaina Getzenberg (@agetzenberg) December 27, 2021
Patriots-Bills is the most likely NFL playoff matchup (57.8% overall and 48.8% in Wild Card Round), per ESPN's FPI.
The Bills have a 66% chance to be the No. 3 seed, while the Patriots have a 53% chance to be the No. 6 seed.
Bills NFL Playoffs
According to ESPN's FPI, the Bills have a 66% chance to finish as the No. 3 seed in the AFC. Of course, Buffalo has two matchups left against a pair of teams currently under .500 (the Atlanta Falcons and New York Jets). Whether they can catch up to the Tennessee Titans remains to be seen.
Meanwhile, the Patriots currently own the second AFC Wild Card spot and have a 53% chance of staying put right there. New England's chances of pulling ahead of the Indianapolis Colts in the standings are not likely given Frank Reich's squad owns the head-to-head tiebreaker.
Despite having a rivalry that dates back to the 1960s, the Bills and Patriots have never met in the playoffs during the Super Bowl era. Watching quarterback Josh Allen duke it out with rookie Mac Jones for the third time in one season would definitely be a joy for even the most casual of NFL fans.
Of course, everything could change in the next two weeks as each squad will look to take care of business. The Bills head into Week 17 as 14-point favorites over the Falcons, while the Patriots are slated as 15.5-point favorites over the Jacksonville Jaguars, according to FanDuel Sportsbook.
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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.