The Duel

Bills vs 49ers Predictions and Expert Picks for Week 13 Monday Night Football

Max Staley
Buffalo Bills vs San Francisco 49ers predictions and expert picks.
Buffalo Bills vs San Francisco 49ers predictions and expert picks. / Timothy T Ludwig/Getty Images
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While Week 12 just wrapped up on Wednesday, the 2020 NFL season continues full steam ahead in Week 13. That includes a two-game Monday Night Football slate, featuring a matchup between two playoff hopefuls, as the Buffalo Bills take on the San Francisco 49ers.

Here's what the experts are predicting for this matchup.

Bills vs 49ers Picks Week 13

WalterFootball picks are from their lead writer, FiveThirtyEight picks are from their NFL Elo game projections, Sporting News picks are from Vinnie Iyer, and betting favorites are from FanDuel Sportsbook's Week 13 NFL odds.

Winner:
WalterFootball: Bills
FiveThirtyEight: Bills
Sporting News: 49ers
Betting Favorite: Bills -1

Against the Spread:
WalterFootball: Bills
Sporting News: 49ers

The majority of the experts are rolling with the Bills to win this one, with only one expert picking San Francisco to cover the spread and pull off the upset.


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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

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