49ers vs Saints Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 10
By Zach Brunner

The San Francisco 49ers hit the road to face the New Orleans Saints at Mercedes-Benz Superdome in Week 10 NFL action on Sunday.
Here's everything you need to know before placing a bet on this game on FanDuel Sportsbook.
49ers vs Saints Point Spread
The 49er are 9.5-point road underdogs. The Saints are 9.5-point home favorites, with -110 odds on both to cover the spread.
49ers vs Saints Over/Under
The over/under for the 49ers vs Saints Week 10 matchup is set at 48.5 total points, with -110 odds on the over and -110 odds on the under.
49ers vs Saints Moneyline
The 49ers vs Saints moneyline has San Francisco as +350 road underdogs, while New Orleans is the -450 favorite at home.
49ers vs Saints Betting Trends
- San Francisco is 2-4 against the spread (ATS) in its last six games.
- San Francisco is 5-1-1 ATS in its last seven games against New Orleans.
- New Orleans is 2-5 ATS in its last seven games.
- The total has hit the over in seven of New Orleans' last eight games.
49ers vs Saints Odds
All NFL betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: SF: (+350) | NO: (-450)
Spread: SF: +9.5 (-110) | NO: -9.5 (-110)
Total: 48.5 – Over: (-110) | Under: (-110)
Public (Spread) Betting Percentages via oddsFire: SF: (38%) | NO: (62%)
Odds to Win Super Bowl LV: SF: (+5500) | NO: (+750)
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