Week 5's slate of NFL games includes a clash between the San Francisco 49ers and Arizona Cardinals.
49ers vs Cardinals Prediction and Pick
ESPN picks are from their Football Power Index (FPI) matchup predictor, numberFire picks are from their analytics projection models, FiveThirtyEight picks are from their NFL projections and betting favorites are according to FanDuel Sportsbook's 49ers-Cardinals betting odds and lines.
NFL Week 5 Picks Straight Up
Betting Favorite: Cardinals (-5)
Cardinals vs 49ers Prediction
Winner: Cardinals (4)
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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.