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Red Sox vs Astros Prediction and Pick for ALCS Game 6 Tonight From FanDuel Sportsbook - October 22

Larry Rupp
Boston Red Sox vs Houston Astros prediction and pick for ALCS game 6.
Boston Red Sox vs Houston Astros prediction and pick for ALCS game 6. / Elsa/GettyImages
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The October 22 slate of MLB games includes a Game 6 clash between the Boston Red Sox and Houston Astros.

Red Sox vs Astros Prediction and Pick Tonight, Oct. 22

CBS Sports picks are from their daily expert picks, FiveThirtyEight picks are from their daily MLB projections, numberFire picks are from their projection models and betting favorites are from FanDuel Sportsbook's Red Sox-Astros betting odds.

MLB Picks Straight Up - 10/22

FiveThirtyEight: Astros
numberFire: Astros
Betting Favorite: Astros (-116)

MLB Moneyline Pick - 10/22

CBS Sports: Astros

Astros vs Red Sox Predictions Game 6

Winner: Astros (3)
Moneyline Pick: Astros (1)


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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