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Rams vs 49ers Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 10 Monday Night Football

Devon Platana
Los Angeles Rams vs San Francisco 49ers prediction, odds, spread, over/under and betting trends for NFL Week 10 game.
Los Angeles Rams vs San Francisco 49ers prediction, odds, spread, over/under and betting trends for NFL Week 10 game. / Harry How/GettyImages
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Rams vs 49ers Week 10 Game Info

NFL Regular Season — Week 10 Game
Los Angeles Rams (7-2, 4-0 Away) vs. San Francisco 49ers (3-5, 0-4 Home)
Date: Monday, November 15, 2021
Time: 8:15 p.m. EST
Venue: Levi's Stadium — Santa Clara, CA
Coverage: ESPN

Rams vs 49ers Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LAR: (-200) | SF: (+168)
Spread: LAR: -4 (-110) | SF: +4 (-110)
Total: 49.5 — Over: (-108) | Under: (-112)
Odds to Win Super Bowl LVI: LAR: (+750) | SF: (+12000)

Rams vs 49ers Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: Los Angeles Rams Win (54.0%)

Rams vs 49ers Betting Trends

- The Rams are 3-8 against the spread (ATS) in their last 11 games against San Francisco.
- San Francisco is 1-5 ATS in its last six games this season.
- The total has hit the under in six of the Rams' last nine games against NFC West opponents.
- The total has hit the under in six of San Francisco's last eight home games against the Rams.

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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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