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Panthers vs Bills Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 15 Game

Devon Platana
Panthers vs Bills point spread, over/under, moneyline and betting trends for Week 15 NFL game.
Panthers vs Bills point spread, over/under, moneyline and betting trends for Week 15 NFL game. / Timothy T Ludwig/GettyImages
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Week 15's slate of games includes a showdown between the Carolina Panthers and Buffalo Bills.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Panthers vs Bills Point Spread

The Bills are 12.5-point home favorites against the Panthers. Buffalo is -110 to cover the spread, while Carolina is -110 to cover as a 12.5-point underdog.

Panthers vs Bills Over/Under

The over/under for the Panthers vs Bills Week 15 NFL matchup is set at 44, with -110 odds on the over and -110 odds on the under.

Panthers vs Bills Moneyline

The Panthers vs Bills moneyline has Buffalo as a -650 favorite, while Carolina is a +480 underdog on the road.

Panthers vs Bills Betting Trends

- Carolina is 2-8 straight up in its last 10 games.
- Buffalo is 4-2-1 against the spread (ATS) in its last seven games against Carolina.
- Carolina is 10-3 ATS in its last 13 road games.
- The total has hit the over in four of Buffalo's last six games played on Sunday.

Panthers vs Bills Prediction

All NFL predictions and picks are from numberFire's projection model.
Prediction: Buffalo Bills win (79.2%)

Panthers vs Bills Odds

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: CAR: (+480) | BUF: (-138)
Spread: CAR: +12.5 (-110) | BUF: -12.5 (-110)
Total: 44 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: CAR: (+1300) | BUF: (+10000)


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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