Astros vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for May 27
By Duel Staff

The Houston Astros will face the Seattle Mariners in MLB action on Friday.
All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.
Astros vs Mariners Game Info
- Houston Astros (29-16) vs. Seattle Mariners (18-27)
- Date: Friday, May 27, 2022
- Time: 9:40 PM ET
- Venue: T-Mobile Park -- Seattle, Washington
Astros vs Mariners Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: HOU: (-194) | SEA: (+162)
- Spread: HOU: -1.5 (-118) | SEA: +1.5 (-102)
- Total: 7 -- Over: (-122) | Under: (+100)
Astros vs Mariners Probable Starting Pitchers
The Houston Astros will give the start to Justin Verlander (6-1, 4.98 ERA) looking for win No. 7 on the season, and the Mariners will turn to Chris Flexen (1-6, 4.98).
Astros vs Mariners Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (53.0%)
Astros vs Mariners Moneyline
- Seattle is the underdog, +162 on the moneyline, while Houston is a -194 favorite despite being on the road.
Astros vs Mariners Spread
- The Astros are 1.5-run road favorites on the runline against the Mariners. The Astros are -118 to cover, and the Mariners are -102.
Astros vs Mariners Over/Under
- An over/under of 7 has been set for Astros-Mariners on May 27, with the over being -122 and the under +100.
Astros vs Mariners Betting Trends
- The Astros have come away with 21 wins in the 31 contests they have been listed as the favorites in this season.
- Houston has been a -190 moneyline favorite on seven occasions this season and won every game.
- Houston and its opponents have gone over the total this season in 11 of their 41 opportunities.
- The Mariners have won 10 of the 31 games they were listed as the moneyline underdog this season (32.3%).
- Seattle has a 2-1 record (winning 66.7% of its games) when it has played as a moneyline underdog of +160 or longer.
- Seattle has combined with opponents to hit the over on the total 24 times this season for a 24-20-1 record against the over/under.
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