NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 11

In a Week 11 NFL slate that includes plenty of exciting contests, the Seattle Seahawks versus the Los Angeles Rams is a game to watch.

Here is the betting info to analyze ahead of Week 11 in the NFL.

Patriots vs. Jets

Breece Hall and the New York Jets (2-7) will get a challenge when they square off against the New England Patriots (8-2), who have the NFL's best run defense, on Thursday, Nov. 13 at 8:15 p.m. ET. Hall ranks 10th-best in the league in rushing yards.

• Game Preview: New York Jets at New England Patriots
• Projected Favorite: Patriots (85.38% win probability)
• Spread: New England (-12.5)
• Total: 43.5 -- Over: (+100) | Under: (-122)
• Time: 8:15 p.m. ET
• Channel: Amazon Prime Video

Bet on New England vs. New York with FanDuel Sportsbook.

Dolphins vs. Commanders

Against the Washington Commanders (3-7), who own the 31st-ranked pass defense this season, Jaylen Waddle and the Miami Dolphins (3-7) shouldn't have any trouble moving the ball through the air when the two teams come together on Sunday, Nov. 16 at 9:30 a.m. ET. Waddle has been one of the NFL's top pass-catchers this season, ranking 10th-best in the league in receiving yards.

• Game Preview: Washington Commanders vs. Miami Dolphins
• Projected Favorite: Dolphins (54.62% win probability)
• Spread: Miami (-2.5)
• Total: 47.5 -- Over: (-104) | Under: (-118)
• Time: 9:30 a.m. ET
• Channel: NFL Network

Bet on Miami vs. Washington with FanDuel Sportsbook.

Vikings vs. Bears

On Sunday, Nov. 16 at 1 p.m. ET, the Minnesota Vikings (4-5) will look to rebound from their recent 27-19 loss to the Ravens when they go head to head against the Chicago Bears (6-3) at U.S. Bank Stadium. The Bears won their previous contest 24-20 versus the Giants.

• Game Preview: Chicago Bears at Minnesota Vikings
• Projected Favorite: Bears (57.66% win probability)
• Spread: Minnesota (-2.5)
• Total: 47.5 -- Over: (-120) | Under: (-102)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Minnesota vs. Chicago with FanDuel Sportsbook.

Steelers vs. Bengals

Ja'Marr Chase and the Cincinnati Bengals (3-6) play the Pittsburgh Steelers (5-4) on Sunday at 1 p.m. ET at Acrisure Stadium.

• Game Preview: Cincinnati Bengals at Pittsburgh Steelers
• Projected Favorite: Steelers (64.65% win probability)
• Spread: Pittsburgh (-5.5)
• Total: 48.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Pittsburgh vs. Cincinnati with FanDuel Sportsbook.

Falcons vs. Panthers

The Atlanta Falcons (3-6) and their 29th-ranked run defense might struggle to stop the Carolina Panthers (5-5) and Rico Dowdle, one of the NFL's top runners, when the Falcons host the Panthers at Mercedes-Benz Stadium on Nov. 16 at 1 p.m. ET.

• Game Preview: Carolina Panthers at Atlanta Falcons
• Projected Favorite: Falcons (58.50% win probability)
• Spread: Atlanta (-3.5)
• Total: 41.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Atlanta vs. Carolina with FanDuel Sportsbook.

Jaguars vs. Chargers

Against the Jacksonville Jaguars (5-4), who have the 28th-ranked pass defense this season, Justin Herbert and the Los Angeles Chargers (7-3) should have success moving the ball through the air when the two teams come together on Sunday, Nov. 16 at 1 p.m. ET. Herbert has been one of the NFL's top passers this year, ranking third-best in the league in passing yards.

• Game Preview: Los Angeles Chargers at Jacksonville Jaguars
• Projected Favorite: Chargers (63.26% win probability)
• Spread: Los Angeles (-3)
• Total: 43.5 -- Over: (-104) | Under: (-118)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Jacksonville vs. Los Angeles with FanDuel Sportsbook.

Giants vs. Packers

One of the best running backs in football will be featured when Josh Jacobs and the Green Bay Packers (5-3-1) visit the New York Giants (2-8) on Sunday, November 16, 2025.

• Game Preview: Green Bay Packers at New York Giants
• Projected Favorite: Packers (76.59% win probability)
• Spread: Green Bay (-7.5)
• Total: 41.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on New York vs. Green Bay with FanDuel Sportsbook.

Titans vs. Texans

The Tennessee Titans (1-8) play on Sunday at 1 p.m. ET at Nissan Stadium against the Houston Texans (4-5).

• Game Preview: Houston Texans at Tennessee Titans
• Projected Favorite: Texans (79.55% win probability)
• Spread: Houston (-5.5)
• Total: 37.5 -- Over: (-106) | Under: (-114)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Tennessee vs. Houston with FanDuel Sportsbook.

Bills vs. Buccaneers

Emeka Egbuka and the Tampa Bay Buccaneers (6-3) will get a challenge when they battle the Buffalo Bills (6-3), who own the league's third-best pass D, on Sunday, Nov. 16 at 1 p.m. ET. Egbuka ranks ninth-best in the league in receiving yards.

• Game Preview: Tampa Bay Buccaneers at Buffalo Bills
• Projected Favorite: Bills (74.35% win probability)
• Spread: Buffalo (-6.5)
• Total: 45.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Buffalo vs. Tampa Bay with FanDuel Sportsbook.

Rams vs. Seahawks

On Sunday, Nov. 16 at 4:05 p.m. ET, two of the league's most dangerous offenses will square off, as the Los Angeles Rams (7-2) and their fifth-ranked offense (27.9 points per game) are set to go head to head with the Seattle Seahawks (7-2) and their third-ranked scoring offense (30.6 points per game).

• Game Preview: Seattle Seahawks at Los Angeles Rams
• Projected Favorite: Rams (65.97% win probability)
• Spread: Los Angeles (-3)
• Total: 48.5 -- Over: (-112) | Under: (-108)
• Time: 4:05 p.m. ET
• Channel: FOX

Bet on Los Angeles vs. Seattle with FanDuel Sportsbook.

Cardinals vs. 49ers

The San Francisco 49ers (6-4) visit the Arizona Cardinals (3-6) on Sunday at 4:05 p.m. ET, in a matchup featuring two outstanding pass-catchers in Christian McCaffrey and Trey McBride.

• Game Preview: San Francisco 49ers at Arizona Cardinals
• Projected Favorite: Cardinals (50.73% win probability)
• Spread: San Francisco (-3.5)
• Total: 48.5 -- Over: (-106) | Under: (-114)
• Time: 4:05 p.m. ET
• Channel: FOX

Bet on Arizona vs. San Francisco with FanDuel Sportsbook.

Broncos vs. Chiefs

One of the best pass-catchers in football will be on display when Travis Kelce and the Kansas City Chiefs (5-4) visit the Denver Broncos (8-2) on Sunday, November 16, 2025.

• Game Preview: Kansas City Chiefs at Denver Broncos
• Projected Favorite: Chiefs (56.75% win probability)
• Spread: Kansas City (-4.5)
• Total: 44.5 -- Over: (-115) | Under: (-105)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Denver vs. Kansas City with FanDuel Sportsbook.

Browns vs. Ravens

The Cleveland Browns (2-7) will host the Baltimore Ravens (4-5) on Sunday at 4:25 p.m. ET.

• Game Preview: Baltimore Ravens at Cleveland Browns
• Projected Favorite: Ravens (69.90% win probability)
• Spread: Baltimore (-7.5)
• Total: 37.5 -- Over: (-115) | Under: (-105)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Cleveland vs. Baltimore with FanDuel Sportsbook.

Eagles vs. Lions

After clinching a 10-7 victory against the Packers in their last contest, the Philadelphia Eagles (7-2) will host the Detroit Lions (6-3), who are coming off a 44-22 win over the Commanders, at Lincoln Financial Field. The game is slated for 8:20 p.m. ET on Sunday, Nov. 16.

• Game Preview: Detroit Lions at Philadelphia Eagles
• Projected Favorite: Eagles (60.12% win probability)
• Spread: Philadelphia (-2.5)
• Total: 46.5 -- Over: (-105) | Under: (-115)
• Time: 8:20 p.m. ET
• Channel: NBC/Peacock

Bet on Philadelphia vs. Detroit with FanDuel Sportsbook.

Raiders vs. Cowboys

While the Las Vegas Raiders (2-7) have had trouble finding the end zone consistently, ranking 31st in the NFL in points per game, the Dallas Cowboys (3-5-1) have struggled to stop opponents from racking up points, as they rank 31st in points allowed per game. The two teams will meet on Monday, Nov. 17 at 8:15 p.m. ET.

• Game Preview: Dallas Cowboys at Las Vegas Raiders
• Projected Favorite: Cowboys (54.35% win probability)
• Spread: Dallas (-3.5)
• Total: 50.5 -- Over: (-104) | Under: (-118)
• Time: 8:15 p.m. ET
• Channel: ABC/ESPN

Bet on Las Vegas vs. Dallas with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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