The Cincinnati Bengals were dealt some troubling injury news on Monday after starting running back Joe Mixon was diagnosed with a low-grade ankle sprain.
Joe Mixon Injury Update
According to reports, Mixon is now considered week-to-week with this injury news. He's been phenomenal in 2021, racking up 353 rushing yards and a pair of touchdowns on 83 attempts this season.
Those 83 attempts are the second most of any running back across the league and his potential absence leaves some huge fantasy implications moving forward.
Samaje Perine Fantasy Outlook
First up on the depth chart is Samaje Perine, a five-year NFL veteran. Mixon has dominated Cincinnati's running back snap share this season, making it difficult to gauge Perine's current level of effectiveness.
He's also operated solely as a career running back backup, notching just nine starts throughout his five-year career. His last start came in Week 17 of the 2020 season, however he saw only 9 rushing attempts in a late-season game with zero Bengals implications.
Perine did start 8 games for the Washington Football Team during his rookie campaign and averaged 3.4 yards per carry and 37.7 yards per game.
The only question for Perine is Cincinnati's offensive game plan moving forward. With Mixon, the Bengals rushed 48% of their snaps. But, it wouldn't be surprising to see that number dip if Mixon is out of the lineup.
Chris Evans Fantasy Outlook
Additionally, Perine hasn't seen nearly any action in the passing game. None of Cincinnati's running backs have been asked to do much other than rush the ball. Mixon owns just 9 targets this season and Perine plus third-stringer Chris Evans sit with just 7 combined.
It will be difficult to gauge the Bengals' response if Mixon is ruled out for Week 5 or further. Perine will eat up most of Mixon's absent carries, but the Bengals could easily opt for a pass-heavy attack thanks to weapons Joe Burrow, Ja'Marr Chase, Tee Higgs and Tyler Boyd.
This is a wait-and-see situation for fantasy managers. Perine could be worth stashing on the bench for now and seeing if the Bengals continue with a rush-first attack.
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Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.