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ESPN College GameDay Crew Picks and Predictions for Week 12 With Guest Pickers Twenty One Pilots

David Kaestle
College GameDay picks for Week 12.
College GameDay picks for Week 12. / Steve Limentani/ISI Photos/GettyImages

Where is College GameDay This Week?

ESPN College GameDay is being held in Columbus, OH for the game between the Michigan State Spartans and the Ohio State Buckeyes.

ESPN College GameDay Guest Picker Week 12

Here are the Week 12 ESPN College GameDay crew predictions from Lee Corso, Kirk Herbstreit, Desmond Howard, and guest pickers Twenty One Pilots for the featured game, as well as other matchups from Saturday's slate.

Who is the ESPN College GameDay Guest Picker This Week?

Grammy Award-winning artists/performers Twenty One Pilots will be the College GameDay guest pickers this week.

ESPN College GameDay Picks

Iowa State Cyclones vs No. 13 Oklahoma Sooners, 12 p.m. EST

Desmond Howard: Iowa State
Twenty One Pilots: Oklahoma
Lee Corso: Oklahoma
Kirk Herbstreit: Oklahoma

No. 10 Wake Forest Demon Deacons vs Clemson Tigers, 12 p.m. EST

Desmond Howard: Clemson
Twenty One Pilots: Clemson
Lee Corso: Clemson
Kirk Herbstreit: Clemson

SMU Mustangs vs No. 5 Cincinnati Bearcats, 3:30 p.m. EST

Desmond Howard: Cincinnati
Twenty One Pilots: SMU
Lee Corso: Cincinnati
Kirk Herbstreit: Cincinnati

No. 7 Michigan State Spartans vs Ohio State Buckeyes, 12 p.m. EST

Desmond Howard: Ohio State
Twenty One Pilots: Ohio State
Lee Corso: Ohio State
Kirk Herbstreit: Calling game, no pick

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David Kaestle is not a FanDuel employee. In addition to providing DFS gameplay advice, David also participates in DFS contests on FanDuel using his personal account, username davekaestle. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.