Best College Football Games Week 4: Predictions, Odds, Picks, Best Bets

The No. 9 Illinois Fighting Illini versus the No. 19 Indiana Hoosiers is one of 16 games on the Week 4 college football schedule that feature a ranked team on the field.

Looking for an edge in college football? We analyze the betting odds for all the important matchups below.

For additional insights, check out the latest college football betting picks from FanDuel Research's staff of writers.

Utah vs. Texas Tech

• Matchup: No. 17 Texas Tech Red Raiders at No. 16 Utah Utes
• Projected Favorite: Utah (56.88% win probability)
• Spread: Utah (-3.5)
• Total: 57.5
• Time: 12 p.m. ET
• Date: Sept. 20
• TV Channel: FOX

Bet on Utah vs. Texas Tech with FanDuel Sportsbook.

Tennessee vs. UAB

• Matchup: UAB Blazers at No. 15 Tennessee Volunteers
• Projected Favorite: Tennessee (96.14% win probability)
• Spread: Tennessee (-39.5)
• Total: 69.5
• Time: 12:45 p.m. ET
• Date: Sept. 20
• TV Channel: SEC Network

Bet on Tennessee vs. UAB with FanDuel Sportsbook.

Oregon vs. Oregon State

• Matchup: Oregon State Beavers at No. 6 Oregon Ducks
• Projected Favorite: Oregon (97.55% win probability)
• Spread: Oregon (-34.5)
• Total: 56.5
• Time: 3 p.m. ET
• Date: Sept. 20
• TV Channel: BTN

Bet on Oregon vs. Oregon State with FanDuel Sportsbook.

Notre Dame vs. Purdue

• Matchup: Purdue Boilermakers at No. 24 Notre Dame Fighting Irish
• Projected Favorite: Notre Dame (95.76% win probability)
• Spread: Notre Dame (-24.5)
• Total: 51.5
• Time: 3:30 p.m. ET
• Date: Sept. 20
• TV Channel: NBC

Bet on Notre Dame vs. Purdue with FanDuel Sportsbook.

Oklahoma vs. Auburn

• Matchup: No. 22 Auburn Tigers at No. 11 Oklahoma Sooners
• Projected Favorite: Oklahoma (58.01% win probability)
• Spread: Oklahoma (-6.5)
• Total: 46.5
• Time: 3:30 p.m. ET
• Date: Sept. 20
• TV Channel: ABC

Bet on Oklahoma vs. Auburn with FanDuel Sportsbook.

Florida State vs. Kent State

• Matchup: Kent State Golden Flashes at No. 7 Florida State Seminoles
• Projected Favorite: Florida State (93.38% win probability)
• Spread: Florida State (-44.5)
• Total: 55.5
• Time: 3:30 p.m. ET
• Date: Sept. 20
• TV Channel: ACC Network

Bet on Florida State vs. Kent State with FanDuel Sportsbook.

Ole Miss vs. Tulane

• Matchup: Tulane Green Wave at No. 13 Ole Miss Rebels
• Projected Favorite: Ole Miss (81.20% win probability)
• Spread: Ole Miss (-12.5)
• Total: 61.5
• Time: 3:30 p.m. ET
• Date: Sept. 20
• TV Channel: ESPN

Bet on Ole Miss vs. Tulane with FanDuel Sportsbook.

Nebraska vs. Michigan

• Matchup: No. 21 Michigan Wolverines at Nebraska Cornhuskers
• Projected Favorite: Michigan (55.64% win probability)
• Spread: Michigan (-1.5)
• Total: 47.5
• Time: 3:30 p.m. ET
• Date: Sept. 20
• TV Channel: CBS

Bet on Nebraska vs. Michigan with FanDuel Sportsbook.

Georgia Tech vs. Temple

• Matchup: Temple Owls at No. 18 Georgia Tech Yellow Jackets
• Projected Favorite: Georgia Tech (91.74% win probability)
• Spread: Georgia Tech (-24.5)
• Total: 52.5
• Time: 4:30 p.m. ET
• Date: Sept. 20
• TV Channel: The CW

Bet on Georgia Tech vs. Temple with FanDuel Sportsbook.

Missouri vs. South Carolina

• Matchup: South Carolina Gamecocks at No. 23 Missouri Tigers
• Projected Favorite: South Carolina (50.45% win probability)
• Spread: Missouri (-9.5)
• Total: 48.5
• Time: 7 p.m. ET
• Date: Sept. 20
• TV Channel: ESPN

Bet on Missouri vs. South Carolina with FanDuel Sportsbook.

Indiana vs. Illinois

• Matchup: No. 9 Illinois Fighting Illini at No. 19 Indiana Hoosiers
• Projected Favorite: Indiana (81.64% win probability)
• Spread: Indiana (-6.5)
• Total: 51.5
• Time: 7:30 p.m. ET
• Date: Sept. 20
• TV Channel: NBC

Bet on Indiana vs. Illinois with FanDuel Sportsbook.

Miami (FL) vs. Florida

• Matchup: Florida Gators at No. 4 Miami (FL) Hurricanes
• Projected Favorite: Miami (FL) (72.96% win probability)
• Spread: Miami (FL) (-8.5)
• Total: 51.5
• Time: 7:30 p.m. ET
• Date: Sept. 20
• TV Channel: ABC

Bet on Miami (FL) vs. Florida with FanDuel Sportsbook.

Vanderbilt vs. Georgia State

• Matchup: Georgia State Panthers at No. 20 Vanderbilt Commodores
• Projected Favorite: Vanderbilt (91.98% win probability)
• Time: 7:30 p.m. ET
• Date: Sept. 20
• TV Channel: ESPNU

Bet on Vanderbilt vs. Georgia State with FanDuel Sportsbook.

LSU vs. Southeastern Louisiana

• Matchup: Southeastern Louisiana Lions at No. 3 LSU Tigers
• Projected Favorite: LSU
• Spread: LSU (-48.5)
• Total: 59.5
• Time: 7:45 p.m. ET
• Date: Sept. 20
• TV Channel: SEC Network

Bet on LSU vs. Southeastern Louisiana with FanDuel Sportsbook.

Texas vs. Sam Houston

• Matchup: Sam Houston Bearkats at No. 8 Texas Longhorns
• Projected Favorite: Texas (93.47% win probability)
• Spread: Texas (-39.5)
• Total: 51.5
• Time: 8 p.m. ET
• Date: Sept. 20
• TV Channel: SEC Network+

Bet on Texas vs. Sam Houston with FanDuel Sportsbook.

USC vs. Michigan State

• Matchup: Michigan State Spartans at No. 25 USC Trojans
• Projected Favorite: USC (83.97% win probability)
• Spread: USC (-18.5)
• Total: 55.5
• Time: 11 p.m. ET
• Date: Sept. 20
• TV Channel: FOX

Bet on USC vs. Michigan State with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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