Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 11

Odds updated as of 1:11 p.m.

MLB action on Thursday includes the Tampa Bay Rays facing the Chicago White Sox.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Rays vs White Sox Game Info

• Tampa Bay Rays (72-73) vs. Chicago White Sox (56-90)
• Date: Thursday, September 11, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and FDSSUN

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-130) | CHW: (+110)
• Spread: TB: -1.5 (+126) | CHW: +1.5 (-152)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Ian Seymour (Rays) - 3-1, 2.89 ERA vs Shane Smith (White Sox) - 5-7, 3.95 ERA

The probable pitchers are Ian Seymour (3-1) for the Rays and Shane Smith (5-7) for the White Sox. Seymour has a record of 2-0-0 ATS in two starts with a spread this season. Seymour's team won his only start as a favorite this season. The White Sox have a 13-12-0 record against the spread in Smith's starts. The White Sox have been the moneyline underdog in 23 of Smith's starts this season, and they went 7-16 in those matchups.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (66.9%)

Rays vs White Sox Moneyline

• Tampa Bay is the favorite, -130 on the moneyline, while Chicago is a +110 underdog despite being at home.

Rays vs White Sox Spread

• The Rays are 1.5-run road favorites on the runline against the White Sox. The Rays are +126 to cover, and the White Sox are -152.

Rays vs White Sox Over/Under

• The over/under for Rays-White Sox on Sept. 11 is 7.5. The over is -120, and the under is -102.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have won in 39, or 57.4%, of the 68 contests they have been named as odds-on favorites in this year.
• Tampa Bay has a record of 24-22 in contests when bookmakers favor them by -130 or more on the moneyline.
• The Rays and their opponents have gone over the total this season in 61 of their 140 opportunities.
• The Rays are 61-79-0 against the spread in their 140 games with a line set by sportsbooks this season.
• The White Sox have won 52 of the 138 games they were the moneyline underdog this season (37.7%).
• Chicago has gone 47-79 when it has played as a moneyline underdog with odds of +110 or longer (37.3%).
• The White Sox have played in 141 games with a set over/under, and have combined with their opponents to go over the total 67 times (67-66-8).
• The White Sox have put together an 81-60-0 record against the spread this season (covering 57.4% of the time).

Rays Player Leaders

• Junior Caminero leads Tampa Bay with 144 hits, batting .263 this season with 69 extra-base hits. He has an on-base percentage of .302 and a slugging percentage of .542.
• Among qualified hitters in MLB, his batting average ranks 62nd, his on-base percentage ranks 123rd, and he is ninth in slugging.
• Caminero hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .250 with two doubles, two home runs and three RBIs.
• Yandy Diaz is slashing .292/.350/.474 this season and leads the Rays with an OPS of .824.
• He is 11th in batting average, 38th in on-base percentage and 35th in slugging in the major leagues.
• Brandon Lowe has 119 hits this season and has a slash line of .259/.311/.479.
• Chandler Simpson is batting .284 with a .316 OBP and 23 RBI for Tampa Bay this season.

White Sox Player Leaders

• Miguel Vargas a has .314 on-base percentage to lead the White Sox. He's batting .234 while slugging .403.
• He ranks 129th in batting average, 107th in on-base percentage and 103rd in slugging percentage among all qualified batters in the big leagues.
• Andrew Benintendi leads his team with 100 hits. He has a batting average of .248 while slugging .438 with an on-base percentage of .311.
• Including all qualifying players, he ranks 94th in batting average, 111th in on-base percentage and 73rd in slugging percentage.
• Lenyn Sosa has a team-high .436 slugging percentage.
• Chase Meidroth is batting .265 with 15 doubles, four home runs and 41 walks.

Rays vs White Sox Head to Head

• 9/10/2025: 6-5 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/9/2025: 5-4 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/23/2025: 11-9 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/27/2024: 8-7 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/26/2024: 9-4 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +194)

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