Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 8:12 a.m.

The MLB's Wednesday slate includes the Tampa Bay Rays taking on the Chicago White Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Rays vs White Sox Game Info

• Tampa Bay Rays (72-72) vs. Chicago White Sox (55-90)
• Date: Wednesday, September 10, 2025
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and FDSSUN

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-142) | CHW: (+120)
• Spread: TB: -1.5 (+118) | CHW: +1.5 (-142)
• Total: 8 -- Over: (-105) | Under: (-115)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Griffin Jax (Rays) - 1-7, 4.81 ERA vs TBA (White Sox)

The Rays will give the ball to Griffin Jax (1-7), while the White Sox's starting pitcher has not yet been announced. Jax and his team failed to cover the spread in his only opportunity this season as a starter. Jax's team lost his only start as a favorite this season.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (69.1%)

Rays vs White Sox Moneyline

• Tampa Bay is a -142 favorite on the moneyline, while Chicago is a +120 underdog at home.

Rays vs White Sox Spread

• The Rays are at the White Sox and are favored by 1.5 runs on the spread. The Rays are +118 to cover the runline, with the White Sox being -142.

Rays vs White Sox Over/Under

• The over/under for the Rays versus White Sox contest on Sept. 10 has been set at 8, with -105 odds on the over and -115 odds on the under.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have come away with 39 wins in the 67 contests they have been listed as the favorites in this season.
• This season Tampa Bay has come away with a win 16 times in 32 chances when named as a favorite of at least -142 on the moneyline.
• The Rays and their opponents have gone over in 60 of their 139 games with a total set by sportsbooks this season.
• The Rays are 61-78-0 against the spread in their 139 games that had a posted line this season.
• The White Sox have won 51 of the 137 games they were the underdog on the moneyline this season (37.2%).
• Chicago is 37-68 (winning only 35.2% of its games) when it has played as a moneyline underdog of +120 or longer.
• The White Sox have played in 140 games with an over/under set, and have combined with their opponents to go over the total 66 times (66-66-8).
• The White Sox have put together an 80-60-0 record ATS this season (covering 57.1% of the time).

Rays Player Leaders

• Junior Caminero leads Tampa Bay with 142 hits, batting .261 this season with 67 extra-base hits. He has an on-base percentage of .301 and a slugging percentage of .535.
• Among the qualifying hitters in MLB, his batting average ranks 70th, his on-base percentage ranks 123rd, and he is 11th in slugging.
• Caminero has hit safely in two straight games. During his last five outings he is hitting .200 with a double, a home run and an RBI.
• Yandy Diaz has a slash line of .290/.348/.468 this season and a team-best OPS of .816.
• Among all qualifying hitters, he is 13th in batting average, 40th in on-base percentage and 42nd in slugging percentage.
• Brandon Lowe has collected 119 base hits, an OBP of .314 and a slugging percentage of .485 this season.
• Chandler Simpson has no home runs, but 23 RBI and a batting average of .287 this season.
• Simpson takes a two-game hitting streak into this game. During his last five outings he is hitting .250 with an RBI.

White Sox Player Leaders

• Andrew Benintendi is batting .248 with 16 doubles, two triples, 18 home runs and 37 walks. He's slugging .433 with an on-base percentage of .312.
• Benintendi brings a four-game hitting streak into this game. In his last five games he is hitting .294 with a double, a home run, three walks and five RBIs.
• Lenyn Sosa leads his team with 123 hits and has a club-best .435 slugging percentage. He has a batting average of .265 with an on-base percentage of .297.
• He is 54th in batting average, 128th in on-base percentage and 76th in slugging percentage in MLB.
• Chase Meidroth is batting .265 with 15 doubles, four home runs and 41 walks.
• Mike Tauchman is batting .270 with 15 doubles, a triple, eight home runs and 41 walks.

Rays vs White Sox Head to Head

• 9/9/2025: 5-4 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/23/2025: 11-9 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/27/2024: 8-7 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/26/2024: 9-4 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/30/2023: 12-9 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

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