Jaguars vs Texans Prediction, Odds, Picks, Best Bets for NFL Week 3

On Sunday in the NFL, the Jacksonville Jaguars are playing the Houston Texans.
Get the latest NFL odds ahead of this game on FanDuel Sportsbook.
Jaguars vs Texans Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Jaguars win (50.6%)
Jaguars vs Texans Point Spread
The Jaguars are 2.5-point favorites against the Texans. The Jaguars are -110 to cover the spread, while the Texans are -110 to cover as a 2.5-point underdog.
Jaguars vs Texans Over/Under
The Jaguars-Texans matchup on Sept. 21 has been given an over/under of 44.5 points. The over is -104 and the under is -118.
Jaguars vs Texans Moneyline
The Jaguars vs Texans moneyline has Jacksonville as a -142 favorite, while Houston is a +120 underdog on the road.
Jaguars vs Texans Betting Trends
- Jacksonville has one win against the spread this year.
- The Jaguars are unbeaten ATS (1-0) as a 2.5-point favorite or greater this season.
- One Jaguars game (out of two) has gone over the point total this season.
- The Texans haven't won a game against the spread this season.
- Houston has no wins ATS (0-1) as a 2.5-point underdog or more this season.
- None of the Texans' two games has hit the over in 2025.
Check out even more in-depth Jaguars vs. Texans analysis on FanDuel Research.
Jaguars vs Texans Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: JAX: (-142) | HOU: (+120)
- Spread: JAX: -2.5 (-110) | HOU: +2.5 (-110)
- Total: 44.5 -- Over: (-104) | Under: (-118)
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