Indiana vs Old Dominion Prediction, Odds, Picks, Best Bets for Week 1 2025

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The Indiana Hoosiers are among the college football squads playing on Saturday, up against the Old Dominion Monarchs.

We've got you covered, in terms of the vital info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Indiana vs Old Dominion Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Indiana: (-3030) | Old Dominion: (+1200)
Spread: Indiana: -23.5 (-115) | Old Dominion: +23.5 (-105)
Total: 54.5 -- Over: (-110) | Under: (-110)

Indiana was 9-4-0 against the spread last season.
As 23.5-point or greater favorites, Indiana went 3-1 against the spread last year.
In 13 Indiana games last season, nine hit the over.
Old Dominion's record against the spread last season was 6-6-0.
In 12 Old Dominion games last year, seven of them went over the total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Hoosiers win (95.8%)

Old Dominion is listed as an underdog by 23.5 points (-105 odds), and Indiana, the favorite, is -115 to cover.

Indiana versus Old Dominion, on Aug. 30, has an over/under of 54.5, with the over being -110 and the under -110.

Looking at the moneyline for Old Dominion-Indiana, Old Dominion is the underdog at +1200, and Indiana is -3030.

The Hoosiers' average implied point total last season was 5.7 fewer points than their implied total in Saturday's game (33.3 implied points on average compared to 39 implied points in this game).
The average implied point total last season for the Monarchs (30.2) is 14.2 more points than the team's implied total in this matchup (16).

Check out even more in-depth Indiana vs. Old Dominion analysis on FanDuel Research.

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