Giants vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 9:12 p.m.

MLB action on Monday includes the San Francisco Giants taking on the Arizona Diamondbacks.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this matchup.

Giants vs Diamondbacks Game Info

• San Francisco Giants (72-71) vs. Arizona Diamondbacks (72-72)
• Date: Monday, September 8, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: Fox Sports 1, NBCS-BA, and ARID

Giants vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-174) | ARI: (+146)
• Spread: SF: -1.5 (+118) | ARI: +1.5 (-142)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Giants vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 13-9, 3.17 ERA vs Nabil Crismatt (Diamondbacks) - 2-0, 2.14 ERA

The Giants will give the nod to Logan Webb (13-9, 3.17 ERA), who is eyeing win No. 14 on the season, and the Diamondbacks will turn to Nabil Crismatt (2-0, 2.14 ERA). Webb's team is 13-16-0 against the spread this season in his starts. When Webb starts a game and his team is the favorite on the moneyline, they have a record of 13-13. The Diamondbacks are 2-1-0 ATS in Crismatt's three starts with a set spread. The Diamondbacks were the underdog on the moneyline for one Crismatt start this season -- they won.

Giants vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (57.2%)

Giants vs Diamondbacks Moneyline

• Arizona is the underdog, +146 on the moneyline, while San Francisco is a -174 favorite at home.

Giants vs Diamondbacks Spread

• The Diamondbacks are at +1.5 on the runline against the Giants. The Diamondbacks are -142 to cover the spread, and the Giants are +118.

Giants vs Diamondbacks Over/Under

• The over/under for the Giants versus Diamondbacks game on Sept. 8 has been set at 7.5, with -118 odds on the over and -104 odds on the under.

Bet on San Francisco Giants vs. Arizona Diamondbacks on FanDuel today!

Giants vs Diamondbacks Betting Trends

• The Giants have been favorites in 85 games this season and have come away with the win 45 times (52.9%) in those contests.
• This year San Francisco has won 10 of 19 games when listed as at least -174 on the moneyline.
• The Giants' games have gone over the total in 67 of their 142 opportunities.
• The Giants are 66-76-0 against the spread in their 142 games that had a posted line this season.
• The Diamondbacks have won 49.1% of the games this season they were the underdog on the moneyline (28-29).
• When playing as a moneyline underdog with odds of +146 or longer, Arizona has a 2-3 record (winning 40% of its games).
• The Diamondbacks have played in 140 games with a set over/under, and have combined with opponents to go over the total 69 times (69-65-6).
• The Diamondbacks have collected a 69-71-0 record against the spread this season (covering 49.3% of the time).

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.380) and total hits (141) this season. He's batting .263 batting average while slugging .492.
• Among qualifying hitters in baseball, he is 67th in batting average, ninth in on-base percentage, and 25th in slugging.
• Jung Hoo Lee has 30 doubles, 11 triples, seven home runs and 44 walks. He's batting .267 and slugging .411 with an on-base percentage of .329.
• Among all qualifying players, he ranks 48th in batting average, 76th in on-base percentage and 89th in slugging percentage.
• Willy Adames is batting .228 with a .425 slugging percentage and 78 RBI this year.
• Heliot Ramos leads San Francisco in slugging percentage (.401) thanks to 40 extra-base hits.

Diamondbacks Player Leaders

• Geraldo Perdomo has a .447 slugging percentage, which paces the Diamondbacks. He's batting .284 with an on-base percentage of .382.
• Including all qualifying hitters in the majors, his batting average places him 19th, his on-base percentage ranks seventh, and he is 63rd in slugging.
• Corbin Carroll's 131 hits pace his team. He has a batting average of .259 while slugging .558 with an on-base percentage of .336.
• Including all qualified hitters, his batting average puts him 79th, his on-base percentage is 63rd, and he is sixth in slugging.
• Ketel Marte has put up a team-high .386 on-base percentage.
• Gabriel Moreno has 11 doubles, a triple, seven home runs and 17 walks while batting .277.

Giants vs Diamondbacks Head to Head

• 7/3/2025: 7-2 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/2/2025: 6-5 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/1/2025: 8-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/30/2025: 4-2 ARI (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/14/2025: 8-7 ARI (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/13/2025: 10-6 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/12/2025: 2-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/25/2024: 8-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 9/24/2024: 11-0 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/23/2024: 6-3 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)

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