Yankees vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 7:15 p.m.

The New York Yankees will face the Minnesota Twins in MLB action on Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this matchup.

Yankees vs Twins Game Info

• New York Yankees (84-67) vs. Minnesota Twins (66-85)
• Date: Wednesday, September 17, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and Amazon Prime Video

Yankees vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-156) | MIN: (+132)
• Spread: NYY: -1.5 (-102) | MIN: +1.5 (-118)
• Total: 9 -- Over: (-122) | Under: (-100)

Yankees vs Twins Probable Starting Pitchers

Probable Pitchers: Luis Gil (Yankees) - 4-1, 2.83 ERA vs Taj Bradley (Twins) - 6-7, 4.88 ERA

This contest's pitching matchup is set, as the Yankees will send Luis Gil (4-1) to the mound, while Taj Bradley (6-7) will get the nod for the Twins. When Gil starts, his team is 4-4-0 against the spread this season. Gil's team has been victorious in 62.5% of the games he's started as the moneyline favorite with a record of 5-3. When Bradley starts, the Twins are 11-14-0 against the spread. The Twins have a 5-8 record in Bradley's 13 starts this season when they were the moneyline underdog.

Yankees vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (58.5%)

Yankees vs Twins Moneyline

• Minnesota is the underdog, +132 on the moneyline, while New York is a -156 favorite despite being on the road.

Yankees vs Twins Spread

• The Twins are +1.5 on the run line against the Yankees. The Twins are -118 to cover, and the Yankees are -102.

Yankees vs Twins Over/Under

• The over/under for the Yankees versus Twins contest on Sept. 17 has been set at 9, with -122 odds on the over and -100 odds on the under.

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Yankees vs Twins Betting Trends

• The Yankees have been favorites in 127 games this season and have come away with the win 75 times (59.1%) in those contests.
• This year New York has won 45 of 71 games when listed as at least -156 on the moneyline.
• The Yankees and their opponents have gone over in 73 of their 149 games with a total set by sportsbooks this season.
• In 149 games with a line this season, the Yankees have a mark of 68-81-0 against the spread.
• The Twins have won 38.6% of the games this season they were the moneyline underdog (22-35).
• Minnesota is 6-11 (winning only 35.3% of its games) when it has played as a moneyline underdog of +132 or longer.
• The Twins have played in 146 games with an over/under set, and have combined with their opponents to go over the total 70 times (70-69-7).
• The Twins have collected a 71-75-0 record against the spread this season (covering 48.6% of the time).

Yankees Player Leaders

• Aaron Judge has 164 hits and an OBP of .451 to go with a slugging percentage of .676. All three of those stats are best among New York hitters this season. He has a .326 batting average, as well.
• Among all qualifying hitters in baseball, his batting average ranks first, his on-base percentage ranks first, and he is first in slugging.
• Cody Bellinger is hitting .273 with 25 doubles, five triples, 28 home runs and 48 walks, while slugging .490 with an on-base percentage of .328.
• He is 36th in batting average, 75th in on-base percentage and 25th in slugging in the major leagues.
• Trent Grisham is batting .239 with a .466 slugging percentage and 67 RBI this year.
• Jazz Chisholm is batting .244 with a .335 OBP and 75 RBI for New York this season.

Twins Player Leaders

• Byron Buxton has accumulated a team-best OBP (.335) and slugging percentage (.553), and leads the Twins in hits (121, while batting .271).
• He ranks 37th in batting average, 61st in on-base percentage and fifth in slugging percentage among all qualified hitters in the big leagues.
• Trevor Larnach's .411 slugging percentage paces his team. He has a batting average of .254 with an on-base percentage of .328.
• He is 83rd in batting average, 75th in on-base percentage and 88th in slugging percentage in MLB.
• Brooks Lee is hitting .238 with 15 doubles, a triple, 15 home runs and 30 walks.
• Kody Clemens has 11 doubles, three triples, 19 home runs and 28 walks while batting .214.

Yankees vs Twins Head to Head

• 9/16/2025: 10-9 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/15/2025: 7-0 MIN (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 8/12/2025: 9-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 8/11/2025: 6-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/6/2024: 8-5 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/5/2024: 9-5 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/4/2024: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/16/2024: 5-0 NYY (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/15/2024: 4-0 NYY (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/14/2024: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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