Rangers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 7:16 p.m.

The Texas Rangers will face the Houston Astros in MLB action on Wednesday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Rangers vs Astros Game Info

• Texas Rangers (79-73) vs. Houston Astros (83-69)
• Date: Wednesday, September 17, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and RSN

Rangers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TEX: (-136) | HOU: (+116)
• Spread: TEX: -1.5 (+126) | HOU: +1.5 (-152)
• Total: 7.5 -- Over: (-108) | Under: (-112)

Rangers vs Astros Probable Starting Pitchers

Probable Pitchers: Jacob deGrom (Rangers) - 12-7, 2.82 ERA vs Cristian Javier (Astros) - 1-3, 4.78 ERA

The Rangers will call on Jacob deGrom (12-7) against the Astros and Cristian Javier (1-3). deGrom's team is 12-16-0 against the spread in his starts this season. deGrom's team has won 58.3% of his starts when they are favored on the moneyline (14-10). When Javier starts, the Astros are 2-4-0 against the spread. The Astros have been the underdog on the moneyline in four of Javier's starts this season, and they went 2-2 in those games.

Rangers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (51.4%)

Rangers vs Astros Moneyline

• Houston is the underdog, +116 on the moneyline, while Texas is a -136 favorite despite being on the road.

Rangers vs Astros Spread

• The Rangers are favored by 1.5 runs on the road against the Astros. The Rangers are +126 to cover the spread, while the Astros are -152.

Rangers vs Astros Over/Under

• Rangers versus Astros on Sept. 17 has an over/under of 7.5 runs, with the odds on the over -108 and the under set at -112.

Bet on Texas Rangers vs. Houston Astros on FanDuel today!

Rangers vs Astros Betting Trends

• The Rangers have come away with 45 wins in the 71 contests they have been listed as the favorites in this season.
• Texas has a record of 26-13 in contests when bookmakers favor them by -136 or more on the moneyline.
• The Rangers' games have gone over the total in 68 of their 151 opportunities.
• In 151 games with a line this season, the Rangers have a mark of 82-69-0 against the spread.
• The Astros have won 31 of the 54 games they were listed as the moneyline underdog this season (57.4%).
• Houston has a 14-8 record (winning 63.6% of its games) when it has played as a moneyline underdog of +116 or longer.
• The Astros have played in 151 games with a set over/under, and have combined with their opponents to go over the total 69 times (69-78-4).
• The Astros have put together a 76-75-0 record against the spread this season.

Rangers Player Leaders

• Wyatt Langford leads Texas with 117 hits and an OBP of .343 this season. He has a .243 batting average and a slugging percentage of .429.
• Among the qualifying hitters in baseball, his batting average ranks 103rd, his on-base percentage ranks 47th, and he is 75th in slugging.
• Josh Smith has an OPS of .711, fueled by an OBP of .341 and a team-best slugging percentage of .370 this season. He's batting .257.
• His batting average ranks 77th among qualified players, his on-base percentage 51st, and his slugging percentage 131st.
• Smith has picked up at least one hit in two games in a row. During his last five outings he is hitting .316 with a double, two walks and an RBI.
• Adolis Garcia has 113 hits this season and has a slash line of .233/.275/.402.
• Josh Jung has been key for Texas with 111 hits, an OBP of .294 plus a slugging percentage of .395.
• Jung heads into this game on a two-game hitting streak. During his last five outings he is batting .250 with two doubles, a home run, a walk and four RBIs.

Astros Player Leaders

• Jose Altuve has a team-best .440 slugging percentage. He's batting .263 with an on-base percentage of .325.
• Including all qualifying hitters in the big leagues, he ranks 54th in batting average, 83rd in on-base percentage and 65th in slugging percentage.
• Jeremy Pena has racked up 146 hits with a .363 on-base percentage to lead his team in both. He has a batting average of .304 while slugging .466.
• His batting average ranks sixth among all qualified players, his on-base percentage is 16th, and he is 43rd in slugging.
• Yainer Diaz is hitting .257 with 23 doubles, a triple, 19 home runs and 20 walks.
• Christian Walker is hitting .236 with 23 doubles, a triple, 23 home runs and 40 walks.

Rangers vs Astros Head to Head

• 9/16/2025: 6-5 HOU (Favorite: Rangers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/15/2025: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/7/2025: 4-2 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/6/2025: 11-0 HOU (Favorite: Rangers, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/5/2025: 4-3 TEX (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/13/2025: 5-1 TEX (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/11/2025: 7-3 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/18/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/17/2025: 5-1 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!