Mets vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 6:12 p.m.

The New York Mets will face the San Diego Padres in MLB action on Wednesday.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Mets vs Padres Game Info

• New York Mets (78-73) vs. San Diego Padres (82-69)
• Date: Wednesday, September 17, 2025
• Time: 7:10 p.m. ET
• Venue: Citi Field -- Queens, New York
• Coverage: SNY and SDPA

Mets vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-130) | SD: (+110)
• Spread: NYM: -1.5 (+164) | SD: +1.5 (-200)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Mets vs Padres Probable Starting Pitchers

Probable Pitchers: David Peterson (Mets) - 9-5, 3.77 ERA vs Nick Pivetta (Padres) - 13-5, 2.73 ERA

The Mets will give the nod to David Peterson (9-5) against the Padres and Nick Pivetta (13-5). Peterson's team is 8-17-0 against the spread this season in his starts. Peterson's team is 12-7 this season when he starts and they are the moneyline favorite. The Padres have a 16-13-0 record against the spread in Pivetta's starts. The Padres have a 5-3 record in Pivetta's eight starts this season when they were the moneyline underdog.

Mets vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (51.4%)

Mets vs Padres Moneyline

• The Mets vs Padres moneyline has New York as a -130 favorite, while San Diego is a +110 underdog on the road.

Mets vs Padres Spread

• The Padres are +1.5 on the run line against the Mets. The Padres are -200 to cover, and the Mets are +164.

Mets vs Padres Over/Under

• Mets versus Padres on Sept. 17 has an over/under of 7.5 runs, with the odds on the over -100 and the under set at -122.

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Mets vs Padres Betting Trends

• The Mets have been chosen as favorites in 102 games this year and have walked away with the win 59 times (57.8%) in those games.
• This season New York has been victorious 44 times in 80 chances when named as a favorite of at least -130 on the moneyline.
• The Mets and their opponents have gone over the total this season in 67 of their 144 opportunities.
• The Mets are 67-77-0 against the spread in their 144 games that had a posted line this season.
• The Padres have won 30 of the 63 games they were listed as the moneyline underdog this season (47.6%).
• San Diego has a record of 20-23 when it has played as a moneyline underdog with odds of +110 or longer (46.5%).
• The Padres have combined with opponents to hit the over on the total 65 times this season for a 65-81-3 record against the over/under.
• The Padres have an 80-69-0 record against the spread this season (covering 53.7% of the time).

Mets Player Leaders

• Juan Soto leads New York in OBP (.395) and total hits (140) this season. He's batting .262 batting average while slugging .523.
• Among qualified batters in the majors, he ranks 60th in batting average, second in on-base percentage, and 11th in slugging.
• Francisco Lindor leads New York in slugging percentage (.454) thanks to 60 extra-base hits. He's batting .265 with an on-base percentage of .340.
• Among all qualified, he is 48th in batting average, 52nd in on-base percentage and 57th in slugging percentage.
• Lindor has picked up a hit in five games in a row. During his last five outings he is batting .316 with a double, a home run, three walks and an RBI.
• Pete Alonso is batting .268 with a .515 slugging percentage and 118 RBI this year.
• Alonso has recorded at least one base hit in three straight games. In his last five games he is batting .250 with two home runs, a walk and five RBIs.
• Brandon Nimmo is batting .262 with a .327 OBP and 83 RBI for New York this season.
• Nimmo has safely hit in three games in a row. During his last five outings he is hitting .300 with a home run and three RBIs.

Padres Player Leaders

• Fernando Tatis Jr. is hitting .262 with 27 doubles, two triples, 22 home runs and 86 walks. He's slugging .434 with an on-base percentage of .365.
• Including all the qualified hitters in MLB, his batting average is 60th, his on-base percentage is 13th, and he is 71st in slugging.
• Manny Machado's 160 hits lead his team. He has a batting average of .276 while slugging .463 with an on-base percentage of .338.
• Including all qualifying hitters, he ranks 31st in batting average, 56th in on-base percentage and 46th in slugging percentage.
• Luis Arraez has a .386 slugging percentage, which leads the Padres.
• Ramon Laureano is batting .286 with 25 doubles, two triples, 23 home runs and 33 walks.

Mets vs Padres Head to Head

• 9/16/2025: 8-3 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/30/2025: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/29/2025: 7-1 SD (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/28/2025: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/25/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/24/2024: 7-1 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/23/2024: 7-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/22/2024: 8-3 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/16/2024: 11-6 NYM (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2024: 5-1 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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