Yankees vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 4:20 p.m.

The New York Yankees are among the MLB teams busy on Saturday, up against the Boston Red Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Yankees vs Red Sox Game Info

• New York Yankees (82-65) vs. Boston Red Sox (81-67)
• Date: Saturday, September 13, 2025
• Time: 4:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: MLB Network, NESN, and YES

Yankees vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-154) | BOS: (+130)
• Spread: NYY: -1.5 (+106) | BOS: +1.5 (-128)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Yankees vs Red Sox Probable Starting Pitchers

Probable Pitchers: Max Fried (Yankees) - 16-5, 3.02 ERA vs Brayan Bello (Red Sox) - 11-6, 3.12 ERA

The Yankees will give the ball to Max Fried (16-5, 3.02 ERA), who is eyeing win No. 17 on the season, and the Red Sox will counter with Brayan Bello (11-6, 3.12 ERA). Fried's team is 16-13-0 against the spread in his starts this season. Fried's team is 19-10 this season when he starts and they are the moneyline favorite. The Red Sox are 16-9-0 ATS in Bello's 25 starts that had a set spread. The Red Sox have been the moneyline underdog in nine of Bello's starts this season, and they went 3-6 in those games.

Yankees vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (59.3%)

Yankees vs Red Sox Moneyline

• The moneyline numbers for Yankees vs. Red Sox reveal New York as the favorite (-154) and Boston as the underdog (+130) despite being the home team.

Yankees vs Red Sox Spread

• The Red Sox are at +1.5 on the runline against the Yankees. The Red Sox are -128 to cover the spread, and the Yankees are +106.

Yankees vs Red Sox Over/Under

• The over/under for Yankees-Red Sox on Sept. 13 is 8.5. The over is -122, and the under is -100.

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Yankees vs Red Sox Betting Trends

• The Yankees have come away with 73 wins in the 124 contests they have been listed as the favorites in this season.
• New York has a record of 46-26 when favored by -154 or more this year.
• The Yankees and their opponents have gone over the total this season in 71 of their 145 opportunities.
• In 145 games with a line this season, the Yankees have a mark of 67-78-0 against the spread.
• The Red Sox have a 22-26 record in games they were listed as the moneyline underdog (winning 45.8% of those games).
• Boston has a record of 8-10 when it has played as a moneyline underdog with odds of +130 or longer (44.4%).
• The Red Sox have had an over/under set by bookmakers 147 times, and have combined with opponents to go over the total in 69 of those games (69-72-6).
• The Red Sox are 79-68-0 against the spread this season.

Yankees Player Leaders

• Aaron Judge leads New York with 159 hits and an OBP of .444, plus a team-best slugging percentage of .673. He's batting .323.
• Among all qualifying batters in the majors, he ranks first in batting average, first in on-base percentage, and first in slugging.
• Judge will look for his third straight game with a hit in this contest. In his last five games he is hitting .357 with four home runs, five walks and four RBIs.
• Cody Bellinger is hitting .276 with 24 doubles, five triples, 28 home runs and 48 walks, while slugging .498 with an on-base percentage of .333.
• Among all qualifying hitters, he is 29th in batting average, 66th in on-base percentage and 20th in slugging percentage.
• Bellinger heads into this matchup looking to extend his five-game hit streak. In his last five games he is batting .316 with a double, a home run, two walks and four RBIs.
• Trent Grisham is batting .239 with a .465 slugging percentage and 64 RBI this year.
• Jazz Chisholm has 28 home runs, 72 RBI and a batting average of .242 this season.
• Chisholm enters this game on a two-game hitting streak. In his last five games he is batting .294 with two walks and two RBIs.

Red Sox Player Leaders

• Jarren Duran has totaled 146 hits with a .332 on-base percentage and a .441 slugging percentage, all club-highs for the Red Sox. He's batting .257.
• Including all the qualified players in MLB, he is 80th in batting average, 68th in on-base percentage and 67th in slugging percentage.
• Trevor Story is batting .261 with 27 doubles, 24 home runs and 31 walks. He's slugging .440 with an on-base percentage of .308.
• Including all qualified hitters, he is 69th in batting average, 115th in on-base percentage and 68th in slugging percentage.
• Alex Bregman has 27 doubles, 16 home runs and 43 walks while hitting .279.
• Ceddanne Rafaela is batting .241 with 29 doubles, three triples, 16 home runs and 25 walks.

Yankees vs Red Sox Head to Head

• 9/12/2025: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/24/2025: 7-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/23/2025: 12-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/22/2025: 1-0 BOS (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 8/21/2025: 6-3 BOS (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/15/2025: 2-0 BOS (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/14/2025: 4-3 BOS (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/13/2025: 2-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/8/2025: 11-7 BOS (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 6/7/2025: 10-7 BOS (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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