Yankees vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 7:11 p.m.

On Friday in MLB, the New York Yankees are playing the Baltimore Orioles.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Orioles Game Info

• New York Yankees (86-67) vs. Baltimore Orioles (72-81)
• Date: Friday, September 19, 2025
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and YES

Yankees vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-116) | BAL: (-102)
• Spread: NYY: -1.5 (+146) | BAL: +1.5 (-176)
• Total: 9 -- Over: (-110) | Under: (-110)

Yankees vs Orioles Probable Starting Pitchers

Probable Pitchers: Will Warren (Yankees) - 8-7, 4.44 ERA vs Trevor Rogers (Orioles) - 8-2, 1.43 ERA

The Yankees will give the nod to Will Warren (8-7, 4.44 ERA), who is eyeing win No. 9 on the season, and the Orioles will counter with Trevor Rogers (8-2, 1.43 ERA). Warren and his team have a record of 12-19-0 against the spread when he starts. Warren's team has a record of 15-10 this season when he starts and they are the favorite on the moneyline. The Orioles are 11-4-0 against the spread when Rogers starts. The Orioles have a 6-3 record in Rogers' nine starts this season when they were the moneyline underdog.

Yankees vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (65.5%)

Yankees vs Orioles Moneyline

• The moneyline numbers for Yankees vs. Orioles reveal New York as the favorite (-116) and Baltimore as the underdog (-102) despite being the home team.

Yankees vs Orioles Spread

• The Orioles are +1.5 on the run line against the Yankees. The Orioles are -176 to cover, and the Yankees are +146.

Yankees vs Orioles Over/Under

• Yankees versus Orioles, on Sept. 19, has an over/under of 9, with the over being -110 and the under -110.

Bet on New York Yankees vs. Baltimore Orioles on FanDuel today!

Yankees vs Orioles Betting Trends

• The Yankees have come away with 77 wins in the 129 contests they have been listed as the favorites in this season.
• New York has a record of 75-51 when favored by -116 or more this year.
• The Yankees and their opponents have hit the over in 74 of their 151 games with a total set by oddsmakers this season.
• The Yankees are 70-81-0 against the spread in their 151 games that had a posted line this season.
• The Orioles have won 39 of the 86 games they were listed as the moneyline underdog this season (45.3%).
• Baltimore has gone 34-43 when it has played as a moneyline underdog with odds of -102 or longer (44.2%).
• The Orioles have had an over/under set by oddsmakers 150 times, and have combined with opponents to go over the total in 63 of those games (63-83-4).
• The Orioles have gone 72-78-0 ATS this season.

Yankees Player Leaders

• Aaron Judge has 167 hits and an OBP of .453 to go with a slugging percentage of .676. All three of those stats are tops among New York hitters this season. He has a .328 batting average, as well.
• He ranks first in batting average, first in on-base percentage, and first in slugging among qualified batters in the majors.
• Cody Bellinger is hitting .273 with 25 doubles, five triples, 29 home runs and 50 walks, while slugging .493 with an on-base percentage of .331.
• Among qualified hitters, his batting average places him 34th, his on-base percentage 69th, and his slugging percentage 23rd.
• Trent Grisham has 111 hits this season and has a slash line of .239/.347/.475.
• Jazz Chisholm is batting .242 with a .333 OBP and 75 RBI for New York this season.

Orioles Player Leaders

• Gunnar Henderson has racked up 149 hits with a .347 on-base percentage and a .439 slugging percentage, all club-bests for the Orioles. He's batting .273.
• He is 34th in batting average, 41st in on-base percentage and 68th in slugging percentage among all qualifying hitters in the majors.
• Henderson enters this matchup on a three-game hitting streak. In his last five games he is batting .350 with two walks and two RBIs.
• Jackson Holliday is hitting .250 with 21 doubles, three triples, 17 home runs and 53 walks. He's slugging .390 with an on-base percentage of .321.
• Including all qualifying players, he is 92nd in batting average, 92nd in on-base percentage and 114th in slugging percentage.
• Jordan Westburg has nine doubles, a triple, 15 home runs and 17 walks while hitting .264.
• Colton Cowser is batting .199 with 12 doubles, 15 home runs and 22 walks.

Yankees vs Orioles Head to Head

• 9/18/2025: 7-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/22/2025: 4-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 6/21/2025: 9-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/20/2025: 5-3 BAL (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 4/30/2025: 5-4 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/29/2025: 15-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/28/2025: 4-3 BAL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/26/2024: 10-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/25/2024: 9-7 BAL (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/24/2024: 5-3 BAL (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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