UTSA vs Charlotte Prediction, Odds, Picks, Best Bets for Week 12 2025

College football's Saturday slate includes the UTSA Roadrunners facing the Charlotte 49ers.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding today's NCAA football betting odds.

UTSA vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: UTSA: (-1205) | Charlotte: (+750)
• Spread: UTSA: -18.5 (-110) | Charlotte: +18.5 (-110)
• Total: 59.5 -- Over: (-110) | Under: (-110)

UTSA vs Charlotte Betting Trends

• UTSA is 4-5-0 against the spread this season.
• UTSA has yet to lose ATS (1-0) as an 18.5-point favorite or greater this season.
• This season, seven of UTSA's nine games have go over the point total.
• Against the spread, Charlotte is 3-6-0 this year.
• Charlotte has one win ATS (1-2) as an 18.5-point underdog or greater this season.
• Of nine Charlotte games so far this year, six have gone over the total.

UTSA vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Roadrunners win (89.1%)

UTSA vs Charlotte Point Spread

Charlotte is listed as an underdog by 18.5 points (-110 odds), and UTSA, the favorite, is -110 to cover.

UTSA vs Charlotte Over/Under

A total of 59.5 points has been set for the UTSA-Charlotte game on Nov. 15, with the over available at -110 and the under at -110.

UTSA vs Charlotte Moneyline

Charlotte is the underdog, +750 on the moneyline, while UTSA is a -1205 favorite.

UTSA vs. Charlotte Points Insights

UTSA vs. Charlotte Game Info

• Game day: Saturday, November 15, 2025
• Game time: 12 p.m. ET
• TV channel: ESPN+
• Location: Charlotte, North Carolina
• Stadium: Jerry Richardson Stadium

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Check out even more in-depth UTSA vs. Charlotte analysis on FanDuel Research.