UTSA vs Charlotte Prediction, Odds, Picks, Best Bets for Week 12 2025

College football's Saturday schedule includes the UTSA Roadrunners taking on the Charlotte 49ers.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

UTSA vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: UTSA: (-820) | Charlotte: (+570)
• Spread: UTSA: -17.5 (-102) | Charlotte: +17.5 (-120)
• Total: 58.5 -- Over: (-110) | Under: (-110)

UTSA vs Charlotte Betting Trends

• UTSA is 4-5-0 against the spread this year.
• UTSA has covered every time (1-0) as a 17.5-point favorite or greater this season.
• This season, seven of UTSA's nine games have gone over the point total.
• Charlotte is 3-6-0 against the spread this season.
• Charlotte has two wins ATS (2-2) as a 17.5-point underdog or more this year.
• There have been six Charlotte games (out of nine) that went over the total this season.

UTSA vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Roadrunners win (88.4%)

UTSA vs Charlotte Point Spread

UTSA is favored by 17.5 points (-102 to cover) in this matchup. Charlotte, the underdog, is -120.

UTSA vs Charlotte Over/Under

An over/under of 58.5 has been set for UTSA-Charlotte on Nov. 15, with the over being -110 and the under -110.

UTSA vs Charlotte Moneyline

Charlotte is a +570 underdog on the moneyline, while UTSA is a -820 favorite.

UTSA vs. Charlotte Points Insights

UTSA vs. Charlotte Game Info

• Game day: Saturday, November 15, 2025
• Game time: 12 p.m. ET
• TV channel: ESPN+
• Location: Charlotte, North Carolina
• Stadium: Jerry Richardson Stadium

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Check out even more in-depth UTSA vs. Charlotte analysis on FanDuel Research.