Twins vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 7:12 p.m.

Saturday's slate in the MLB includes a matchup between the Minnesota Twins and the Arizona Diamondbacks.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Diamondbacks Game Info

• Minnesota Twins (65-82) vs. Arizona Diamondbacks (73-75)
• Date: Saturday, September 13, 2025
• Time: 7:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and ARID

Twins vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-142) | ARI: (+120)
• Spread: MIN: -1.5 (+146) | ARI: +1.5 (-176)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Twins vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 13-8, 3.32 ERA vs Ryne Nelson (Diamondbacks) - 7-3, 3.48 ERA

This contest's pitching matchup is set, as the Twins will send Joe Ryan (13-8) to the mound, while Ryne Nelson (7-3) will answer the bell for the Diamondbacks. Ryan and his team are 12-14-0 ATS this season when he starts. Ryan's team has won 52.4% of his starts when they are favored on the moneyline (11-10). The Diamondbacks have an 11-9-0 record against the spread in Nelson's starts. The Diamondbacks have been the underdog on the moneyline in eight of Nelson's starts this season, and they went 4-4 in those matchups.

Twins vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (52.7%)

Twins vs Diamondbacks Moneyline

• The moneyline numbers for Twins vs. Diamondbacks reveal Minnesota as the favorite (-142) and Arizona as the underdog (+120) on the road.

Twins vs Diamondbacks Spread

• The Diamondbacks are +1.5 on the run line against the Twins. The Diamondbacks are -176 to cover, and the Twins are +146.

Twins vs Diamondbacks Over/Under

• The over/under for the Twins versus Diamondbacks contest on Sept. 13 has been set at 8.5, with -102 odds on the over and -120 odds on the under.

Bet on Minnesota Twins vs. Arizona Diamondbacks on FanDuel today!

Twins vs Diamondbacks Betting Trends

• The Twins have been chosen as favorites in 84 games this year and have walked away with the win 40 times (47.6%) in those games.
• This year Minnesota has won 19 of 35 games when listed as at least -142 on the moneyline.
• The Twins' games have gone over the total in 68 of their 142 opportunities.
• The Twins have posted a record of 69-73-0 against the spread this season.
• The Diamondbacks have gone 29-32 in games they were the underdog on the moneyline (winning 47.5% of those games).
• Arizona has gone 14-8 when it has played as a moneyline underdog with odds of +120 or longer (63.6%).
• The Diamondbacks have played in 144 games with a set over/under, and have combined with their opponents to go over the total 72 times (72-66-6).
• The Diamondbacks have a 71-73-0 record ATS this season (covering 49.3% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota in OBP (.338) and total hits (118) this season. He's batting .274 batting average while slugging .565.
• He ranks 35th in batting average, 54th in on-base percentage, and fourth in slugging among qualified hitters in MLB.
• Buxton hopes to build on a five-game hitting streak in this matchup. In his last five games he is hitting .375 with a triple, two home runs, a walk and four RBIs.
• Trevor Larnach leads Minnesota in slugging percentage (.405) thanks to 38 extra-base hits. He's batting .254 with an on-base percentage of .326.
• He is 88th in batting average, 81st in on-base percentage and 97th in slugging among qualifying hitters.
• Brooks Lee has collected 104 base hits, an OBP of .287 and a slugging percentage of .369 this season.
• Kody Clemens is batting .213 with a .282 OBP and 48 RBI for Minnesota this season.

Diamondbacks Player Leaders

• Geraldo Perdomo has put up an on-base percentage of .386 and a slugging percentage of .455. Both lead the Diamondbacks. He's batting .285.
• Including all the qualified players in the big leagues, his batting average is 17th, his on-base percentage ranks sixth, and he is 52nd in slugging.
• Perdomo hopes to build on a three-game hitting streak in this matchup. During his last five outings he is hitting .235 with two home runs, four walks and four RBIs.
• Corbin Carroll has collected 133 hits to lead his team. He has a batting average of .256 while slugging .546 with an on-base percentage of .334.
• Including all qualifying hitters, his batting average places him 83rd, his on-base percentage is 62nd, and he is sixth in slugging.
• Ketel Marte has 22 doubles, 25 home runs and 63 walks while hitting .281.
• Gabriel Moreno has 11 doubles, a triple, nine home runs and 20 walks while hitting .290.

Twins vs Diamondbacks Head to Head

• 9/12/2025: 9-8 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/27/2024: 13-6 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/26/2024: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/25/2024: 5-4 ARI (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/5/2023: 12-1 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/4/2023: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/19/2022: 7-1 ARI (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/18/2022: 11-1 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/17/2022: 7-2 ARI (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)

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