Trail Blazers vs. Thunder Prediction, Odds, Picks, Best Bets for Nov. 5

Trail Blazers vs. Thunder Game Info

• Date: Wednesday, November 5, 2025
• Time: 10 p.m. ET
• Venue: Moda Center -- Portland, Oregon
• Coverage: KUNP and FDSOK

The Oklahoma City Thunder (8-0) are favored (by 3.5 points) to extend a four-game road win streak when they visit the Portland Trail Blazers (4-3) on Wednesday, November 5, 2025 at 10 p.m. ET. The over/under for the matchup is set at 231.5.

Trail Blazers vs. Thunder Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Trail Blazers vs. Thunder Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction:

Trail Blazers vs. Thunder Betting Trends

• The Thunder are 4-4-0 against the spread this season.
• The Trail Blazers have played seven games, with five wins against the spread.
• Games involving the Thunder have hit the over five times out of seven chances this season.
• Trail Blazers games this season have hit the over on five of seven set point totals (71.4%).
• When playing at home, Oklahoma City sports an identical winning percentage against the spread as it does in away games (.500).
• The Thunder have gone over the total in three of four home games (75%), compared to two of four road games (50%).

Thunder Leaders

• Shai Gilgeous-Alexander averages 33.1 points, 5 rebounds and 6.6 assists.
• Isaiah Hartenstein is averaging 10.8 points, 10.9 rebounds and 3.5 assists. At the other end, he averages 1.6 steals and 0.4 blocked shots.
• Ajay Mitchell averages 16.1 points, 3.6 rebounds and 3.5 assists.
• Chet Holmgren is averaging 20.6 points, 9.2 boards and 2 assists. Defensively, he averages 1.2 steals and 1.6 blocked shots.
• Aaron Wiggins averages 13.3 points, 3.9 boards and 2.3 assists, shooting 44.6% from the field and 36% from downtown, with 2.3 made 3-pointers per game.

Trail Blazers Leaders

• Deni Avdija's numbers on the season are 24.1 points, 6 rebounds and 3.9 assists per game. He is also sinking 49.1% of his shots from the field and 37.8% from beyond the arc, with an average of 2.4 triples.
• Jrue Holiday's numbers on the season are 16.7 points, 4.7 boards and 8.3 assists per contest. He is sinking 46.9% of his shots from the floor and 31.9% from 3-point range, with an average of 2.1 treys.
• Per game, Jerami Grant gives the Trail Blazers 20.3 points, 3 rebounds and 1.6 assists, plus 1.6 steals and 0.6 blocks.
• Shaedon Sharpe's numbers on the season are 18.1 points, 4.7 boards and 1.6 assists per contest. He is making 36.7% of his shots from the field and 25% from 3-point range, with an average of 1.9 treys.
• The Trail Blazers receive 8.4 points per game from Donovan Clingan, plus 9.1 boards and 1.9 assists.

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