Tigers vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 6:12 p.m.

The MLB's Friday schedule includes the Detroit Tigers taking on the Chicago White Sox.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs White Sox Game Info

• Detroit Tigers (81-60) vs. Chicago White Sox (53-88)
• Date: Friday, September 5, 2025
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: FDSDET and CHSN

Tigers vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-190) | CHW: (+160)
• Spread: DET: -1.5 (+108) | CHW: +1.5 (-130)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Tigers vs White Sox Probable Starting Pitchers

Probable Pitchers: Jack Flaherty (Tigers) - 7-13, 4.74 ERA vs Shane Smith (White Sox) - 4-7, 3.81 ERA

This contest's pitching matchup is set, as the Tigers will send Jack Flaherty (7-13) to the mound, while Shane Smith (4-7) will answer the bell for the White Sox. Flaherty's team is 9-17-0 against the spread in his starts this season. When Flaherty starts a game and his team is the favorite on the moneyline, they have a record of 7-10. The White Sox have gone 12-12-0 against the spread when Smith starts. The White Sox have been the moneyline underdog in 22 of Smith's starts this season, and they went 6-16 in those games.

Tigers vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (68.8%)

Tigers vs White Sox Moneyline

• Detroit is the favorite, -190 on the moneyline, while Chicago is a +160 underdog on the road.

Tigers vs White Sox Spread

• The Tigers are hosting the White Sox and are favored by 1.5 runs (+108 to cover) on the runline. Chicago is -130 to cover.

Tigers vs White Sox Over/Under

• Tigers versus White Sox on Sept. 5 has an over/under of 8.5 runs, with the odds on the over -105 and the under set at -115.

Bet on Detroit Tigers vs. Chicago White Sox on FanDuel today!

Tigers vs White Sox Betting Trends

• The Tigers have been victorious in 56, or 61.5%, of the 91 contests they have been chosen as favorites in this season.
• Detroit has a record of 16-7 when favored by -190 or more this year.
• The Tigers and their opponents have hit the over in 67 of their 135 games with a total set by oddsmakers this season.
• The Tigers are 65-70-0 against the spread in their 135 games with a line set by sportsbooks this season.
• The White Sox have put together a 49-84 record in games they were listed as the moneyline underdog (winning 36.8% of those games).
• In games it has played as a moneyline underdog with odds of +160 or longer, Chicago has a 13-36 record (winning just 26.5% of its games).
• The White Sox have played in 136 games with a set over/under, and have combined with opponents to go over the total 63 times (63-65-8).
• The White Sox have gone 77-59-0 ATS this season.

Tigers Player Leaders

• Riley Greene has 141 hits to go with a slugging percentage of .511, both of which are best among Detroit hitters this season. He has a .269 batting average and an on-base percentage of .324.
• Among qualifying batters in MLB, he ranks 47th in batting average, 88th in on-base percentage, and 16th in slugging.
• Gleyber Torres has 119 hits this season and a team-best OBP of .364. He's batting .261 and slugging .395.
• Among qualifying batters, his batting average ranks him 73rd, his on-base percentage 21st, and his slugging percentage 114th.
• Spencer Torkelson is batting .238 with a .466 slugging percentage and 71 RBI this year.
• Torkelson takes a three-game hitting streak into this game. During his last five outings he is hitting .222 with two walks and an RBI.
• Zach McKinstry has 11 home runs, 46 RBI and a batting average of .267 this season.
• McKinstry takes a four-game hitting streak into this matchup. In his last five games he is batting .429 with a double, a triple, two walks and three RBIs.

White Sox Player Leaders

• Andrew Benintendi is batting .244 with 15 doubles, two triples, 17 home runs and 35 walks. He's slugging .424 with an on-base percentage of .307.
• Lenyn Sosa has 119 hits while slugging .430. Both are team-highs. He has a batting average of .263 with an on-base percentage of .294.
• He ranks 65th in batting average, 138th in on-base percentage and 80th in slugging percentage in the majors.
• Chase Meidroth is batting .258 with 15 doubles, four home runs and 38 walks.
• Mike Tauchman is batting .271 with 15 doubles, a triple, eight home runs and 40 walks.

Tigers vs White Sox Head to Head

• 8/13/2025: 1-0 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/12/2025: 9-6 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 8/11/2025: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/5/2025: 3-2 CHW (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/3/2025: 8-1 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/2/2025: 13-1 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/6/2025: 4-3 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 4/5/2025: 7-2 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 4/4/2025: 7-4 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/29/2024: 9-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)

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