Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 7

Odds updated as of 4:17 a.m.

Sunday's slate in the MLB includes a matchup between the Milwaukee Brewers and the Pittsburgh Pirates.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Brewers vs Pirates Game Info

• Milwaukee Brewers (88-55) vs. Pittsburgh Pirates (64-79)
• Date: Sunday, September 7, 2025
• Time: 1:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and FDSWI

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-154) | PIT: (+130)
• Spread: MIL: -1.5 (+118) | PIT: +1.5 (-142)
• Total: 8 -- Over: (-105) | Under: (-115)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 4-2, 4.50 ERA vs Bubba Chandler (Pirates) - 2-0, 2.25 ERA

The Brewers will look to Jacob Misiorowski (4-2) against the Pirates and Bubba Chandler (2-0). Misiorowski's team is 7-4-0 against the spread in his starts this season. Misiorowski's team is 2-3 this season when he starts and they are the moneyline favorite. Chandler did not pitch as a moneyline underdog a season ago.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (59.2%)

Brewers vs Pirates Moneyline

• Milwaukee is the favorite, -154 on the moneyline, while Pittsburgh is a +130 underdog despite being at home.

Brewers vs Pirates Spread

• The Brewers are at the Pirates and are favored by 1.5 runs (+118 to cover) on the runline. Pittsburgh is -142 to cover.

Brewers vs Pirates Over/Under

• The Brewers-Pirates game on Sept. 7 has been given an over/under of 8 runs. The over is set at -105 and the under at -115.

Bet on Milwaukee Brewers vs. Pittsburgh Pirates on FanDuel today!

Brewers vs Pirates Betting Trends

• The Brewers have been chosen as favorites in 79 games this year and have walked away with the win 52 times (65.8%) in those games.
• This season Milwaukee has been victorious 20 times in 27 chances when named as a favorite of at least -154 on the moneyline.
• The Brewers' games have gone over the total in 69 of their 140 opportunities.
• The Brewers are 80-60-0 against the spread in their 140 games with a line set by sportsbooks this season.
• The Pirates have put together a 41-54 record in games they were listed as the moneyline underdog (winning 43.2% of those games).
• When it has played as a moneyline underdog with odds of +130 or longer, Pittsburgh has an 18-28 record (winning only 39.1% of its games).
• The Pirates have played in 135 games with a set over/under, and have combined with opponents to go over the total 53 times (53-76-6).
• The Pirates have put together a 74-61-0 record ATS this season (covering 54.8% of the time).

Brewers Player Leaders

• William Contreras is hitting .263 with 26 doubles, 17 home runs and 77 walks. He has an on-base percentage of .359 while slugging .411.
• He is 64th in batting average, 25th in on-base percentage, and 95th in slugging among all qualified hitters in baseball.
• Contreras has recorded a base hit in six straight games. During his last 10 outings he is batting .293 with two doubles, two home runs, three walks and four RBIs.
• Brice Turang leads Milwaukee in slugging percentage (.447) thanks to 44 extra-base hits. He's batting .291 with an on-base percentage of .358.
• His batting average is 14th among qualified players, his on-base percentage 26th, and his slugging percentage 66th.
• Turang brings a two-game streak with at least one hit into this matchup. In his last five games he is hitting .438 with a double, a triple, a home run, three walks and three RBIs.
• Christian Yelich has collected 134 base hits, an OBP of .350 and a slugging percentage of .464 this season.
• Jackson Chourio leads Milwaukee in total hits (130) this season while batting .275 with 54 extra-base hits.

Pirates Player Leaders

• Bryan Reynolds has a slugging percentage of .412 and has 129 hits, both team-best figures for the Pirates. He's batting .247 and with an on-base percentage of .316.
• He is 99th in batting average, 103rd in on-base percentage and 92nd in slugging percentage among all qualified hitters in the big leagues.
• Oneil Cruz is hitting .203 with 17 doubles, two triples, 19 home runs and 60 walks. He's slugging .388 with an on-base percentage of .305.
• Including all qualified hitters, he ranks 151st in batting average, 123rd in on-base percentage and 121st in slugging percentage.
• Andrew McCutchen a has .339 on-base percentage to pace the Pirates.
• Tommy Pham has 17 doubles, a triple, eight home runs and 39 walks while batting .261.

Brewers vs Pirates Head to Head

• 9/6/2025: 4-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/5/2025: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/13/2025: 12-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/12/2025: 14-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/11/2025: 7-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/25/2025: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/24/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/23/2025: 5-4 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/25/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/24/2025: 2-1 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)

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