Tigers vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 2:12 a.m.

In MLB action on Tuesday, the Detroit Tigers play the Boston Red Sox.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Red Sox Game Info

• Detroit Tigers (18-18) vs. Boston Red Sox (14-21)
• Date: Tuesday, May 5, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: DSN and NESN

Tigers vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-180) | BOS: (+152)
• Spread: DET: -1.5 (+114) | BOS: +1.5 (-137)
• Total: 8 -- Over: (-112) | Under: (-108)

Tigers vs Red Sox Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Tigers) - 2-1, 3.35 ERA vs Jovani Moran (Red Sox) - 0-0, 2.33 ERA

This contest's pitching matchup is set, as the Tigers will send Framber Valdez (2-1) to the mound, while Jovani Moran will take the ball for the Red Sox. Valdez and his team are 5-2-0 ATS this season when he starts. Valdez's team has won 50% of his starts when they are favored on the moneyline (2-2). Moran and his team were underdogs on the moneyline every time he pitched a season ago.

Tigers vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (65%)

Tigers vs Red Sox Moneyline

• Looking at the moneyline for Red Sox-Tigers, Boston is the underdog at +152, and Detroit is -180 playing at home.

Tigers vs Red Sox Spread

• The Red Sox are +1.5 on the run line against the Tigers. The Red Sox are -137 to cover, and the Tigers are +114.

Tigers vs Red Sox Over/Under

• Tigers versus Red Sox on May 5 has an over/under of 8 runs, with the odds on the over -112 and the under set at -108.

Bet on Detroit Tigers vs. Boston Red Sox on FanDuel today!

Tigers vs Red Sox Betting Trends

• The Tigers have been favorites in 23 games this season and have come away with the win 13 times (56.5%) in those contests.
• Detroit has been listed as a favorite of -180 or more on two occasions this season and won both games.
• The Tigers and their opponents have gone over in 17 of their 36 games with a total set by sportsbooks this season.
• The Tigers are 19-17-0 against the spread in their 36 games that had a posted line this season.
• The Red Sox have compiled a 3-8 record in games they were listed as the moneyline underdog (winning 27.3% of those games).
• Boston has yet to play a game with moneyline odds of +152 or longer.
• The Red Sox have combined with opponents to hit the over on the total 17 times this season for a 17-17-1 record against the over/under.
• The Red Sox have put together an 11-24-0 record against the spread this season (covering only 31.4% of the time).

Tigers Player Leaders

• Kevin McGonigle has an OPS of .884, fueled by an OBP of .407 to go with a slugging percentage of .477. He has a .315 batting average, as well.
• Among qualified hitters in baseball, his batting average ranks 15th, his on-base percentage ranks 12th, and he is 41st in slugging.
• McGonigle hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .250 with three walks and four RBIs.
• Riley Greene has nine doubles, four home runs and 21 walks. He's batting .289 and slugging .453 with an on-base percentage of .389.
• Among qualified hitters, he is 36th in batting average, 21st in on-base percentage and 49th in slugging percentage.
• Dillon Dingler leads Detroit in total hits (27) this season, and 13 of those have gone for extra bases.
• Dingler enters this game with four games in a row with at least one hit. In his last five games he is batting .278 with two doubles, a home run and six RBIs.
• Gleyber Torres has been key for Detroit with 30 hits, an OBP of .389 plus a slugging percentage of .328.

Red Sox Player Leaders

• Wilyer Abreu has a team-best .453 slugging percentage. He's batting .297 with an on-base percentage of .379.
• Including all the qualifying hitters in the majors, he ranks 30th in batting average, 32nd in on-base percentage and 49th in slugging percentage.
• Willson Contreras has racked up 33 hits with a .381 OBP to pace his team in both. He has a batting average of .270 while slugging .475.
• Including all qualified players, he ranks 53rd in batting average, 27th in on-base percentage and 42nd in slugging percentage.
• Jarren Duran has five doubles, four home runs and eight walks while batting .203.
• Caleb Durbin is batting .165 with six doubles, a home run and 11 walks.

Tigers vs Red Sox Head to Head

• 5/4/2026: 5-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/20/2026: 8-6 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/19/2026: 6-2 DET (Favorite: Red Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/18/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/17/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/28/2025: 4-3 BOS (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/27/2025: 2-1 DET (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/26/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/14/2025: 6-5 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 5/13/2025: 10-9 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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