SMU vs Missouri State Prediction, Odds, Picks, Best Bets for Week 3 2025

The SMU Mustangs are among the college football squads busy on Saturday, versus the Missouri State Bears.

We've got you covered, in terms of the most important info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

SMU vs Missouri State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SMU: (-4000) | Missouri State: (+1400)
• Spread: SMU: -27.5 (-120) | Missouri State: +27.5 (-102)
• Total: 60.5 -- Over: (-115) | Under: (-105)

SMU vs Missouri State Betting Trends

• SMU has no wins against the spread this season.
• Every SMU game has hit the over this season.
• Missouri State has but one win versus the spread this year.
• Missouri State doesn't have a win ATS (0-1) as a 27.5-point underdog or greater this year.
• One of Missouri State's two games has hit the over.

SMU vs Missouri State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Mustangs win (94.3%)

SMU vs Missouri State Point Spread

SMU is favored by 27.5 points versus Missouri State. SMU is -120 to cover the spread, while Missouri State is -102.

SMU vs Missouri State Over/Under

A combined point total of 60.5 has been set for SMU-Missouri State on Sept. 13, with the over at -115 and the under at -105.

SMU vs Missouri State Moneyline

SMU is the favorite, -4000 on the moneyline, while Missouri State is a +1400 underdog.

SMU vs. Missouri State Points Insights

SMU vs. Missouri State Game Info

• Game day: Saturday, September 13, 2025
• Game time: 3:30 p.m. ET
• TV channel: CBS Sports Network
• Location: Springfield, Missouri
• Stadium: Robert W. Plaster Stadium

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Check out even more in-depth SMU vs. Missouri State analysis on FanDuel Research.