San Diego State vs Wyoming Prediction, Odds, Picks, Best Bets for Week 10 2025

The San Diego State Aztecs versus the Wyoming Cowboys is on the college football schedule for Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding today's NCAA football betting odds.

San Diego State vs Wyoming Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: San Diego State: (-429) | Wyoming: (+340)
• Spread: San Diego State: -10.5 (-110) | Wyoming: +10.5 (-110)
• Total: 41.5 -- Over: (-115) | Under: (-105)

San Diego State vs Wyoming Betting Trends

• San Diego State has six wins in seven games against the spread this season.
• San Diego State has covered every time (1-0) as a 10.5-point favorite or greater this season.
• This year, three of San Diego State's seven games have hit the over.
• Against the spread, Wyoming is 5-3-0 this season.
• Wyoming has no wins ATS (0-2) as a 10.5-point underdog or more this year.
• A pair of Wyoming eight games in 2025 have hit the over.

San Diego State vs Wyoming Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Aztecs win (72.5%)

San Diego State vs Wyoming Point Spread

Wyoming is a 10.5-point underdog against San Diego State. Wyoming is -110 to cover the spread, and San Diego State is -110.

San Diego State vs Wyoming Over/Under

An over/under of 41.5 has been set for San Diego State-Wyoming on Nov. 1, with the over being -115 and the under -105.

San Diego State vs Wyoming Moneyline

San Diego State is a -429 favorite on the moneyline, while Wyoming is a +340 underdog.

San Diego State vs. Wyoming Points Insights

San Diego State vs. Wyoming Game Info

• Game day: Saturday, November 1, 2025
• Game time: 7 p.m. ET
• TV channel: CBS Sports Network
• Location: San Diego, California
• Stadium: Snapdragon Stadium

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