Royals vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 23

Odds updated as of 9:12 p.m.

The MLB's Tuesday slate includes the Kansas City Royals facing the Los Angeles Angels.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Royals vs Angels Game Info

• Kansas City Royals (78-78) vs. Los Angeles Angels (70-86)
• Date: Tuesday, September 23, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and FDSKC

Royals vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-166) | LAA: (+140)
• Spread: KC: -1.5 (-104) | LAA: +1.5 (-115)
• Total: 9 -- Over: (-114) | Under: (-106)

Royals vs Angels Probable Starting Pitchers

Probable Pitchers: Cole Ragans (Royals) - 2-3, 5.16 ERA vs Samuel Aldegheri (Angels) - 0-0, 10.38 ERA

The probable starters are Cole Ragans (2-3) for the Royals and Samuel Aldegheri for the Angels. Ragans' team is 5-6-0 against the spread this season in his starts. Ragans' team is 5-4 this season when he starts and they are the moneyline favorite. Last season Aldegheri and his team finished 1-2-0 against the spread in games he pitched. Aldegheri and his team put together a 1-2 record in the three games he pitched when they were the underdog on the moneyline a season ago.

Royals vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (62.7%)

Royals vs Angels Moneyline

• Los Angeles is a +140 underdog on the moneyline, while Kansas City is a -166 favorite on the road.

Royals vs Angels Spread

• The Royals are at the Angels and are favored by 1.5 runs (-104 to cover) on the runline. Los Angeles is -115 to cover.

Royals vs Angels Over/Under

• The Royals-Angels game on Sept. 23 has been given an over/under of 9 runs. The over is set at -114 and the under at -106.

Bet on Kansas City Royals vs. Los Angeles Angels on FanDuel today!

Royals vs Angels Betting Trends

• The Royals have been chosen as favorites in 63 games this year and have walked away with the win 36 times (57.1%) in those games.
• This season Kansas City has been victorious 10 times in 14 chances when named as a favorite of at least -166 on the moneyline.
• The Royals and their opponents have gone over in 67 of their 154 games with a total set by sportsbooks this season.
• The Royals are 75-79-0 against the spread in their 154 games with a line set by sportsbooks this season.
• The Angels have compiled a 50-65 record in games they were the underdog on the moneyline (winning 43.5% of those games).
• When playing as a moneyline underdog with odds of +140 or longer, Los Angeles has a 20-25 record (winning 44.4% of its games).
• The Angels have played in 154 games with an over/under set, and have combined with their opponents to go over the total 82 times (82-67-5).
• The Angels have collected an 81-73-0 record against the spread this season (covering 52.6% of the time).

Royals Player Leaders

• Bobby Witt Jr. leads Kansas City with 174 hits and an OBP of .351, plus a team-best slugging percentage of .501. He's batting .292.
• He is 11th in batting average, 34th in on-base percentage, and 16th in slugging among all qualifying batters in the majors.
• Witt hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .304 with two doubles, a home run and three RBIs.
• Vinnie Pasquantino is batting .269 with 30 doubles, a triple, 31 home runs and 48 walks, while slugging .480 with an on-base percentage of .329.
• He ranks 40th in batting average, 73rd in on-base percentage and 31st in slugging in MLB.
• Maikel Garcia leads Kansas City in OBP (.351) this season, fueled by 163 hits.
• Salvador Perez has been key for Kansas City with 138 hits, an OBP of .283 plus a slugging percentage of .456.
• Perez heads into this game on an eight-game hitting streak. In his last 10 games he is hitting .308 with five home runs, two walks and 15 RBIs.

Angels Player Leaders

• Taylor Ward has a .470 slugging percentage, which leads the Angels. He's batting .228 with an on-base percentage of .315.
• Including all qualified hitters in the big leagues, he ranks 138th in batting average, 101st in on-base percentage and 39th in slugging percentage.
• Ward hopes to build on a five-game hitting streak in this matchup. In his last five games he is batting .421 with three home runs and three RBIs.
• Jo Adell paces his team with 119 hits. He has a batting average of .237 while slugging .490 with an on-base percentage of .297.
• His batting average ranks 118th among all qualified players, his on-base percentage is 125th, and he is 20th in slugging.
• Nolan Schanuel has 23 doubles, a triple, 11 home runs and 57 walks while batting .268.
• Mike Trout has a .357 on-base percentage to pace his team.

Royals vs Angels Head to Head

• 9/4/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/3/2025: 4-3 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/2/2025: 5-1 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/21/2024: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 8/20/2024: 9-5 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/19/2024: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/12/2024: 4-2 KC (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/11/2024: 9-3 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/10/2024: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/9/2024: 10-4 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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