Reds vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for April 28

Odds updated as of 2:12 a.m.

MLB action on Tuesday includes the Cincinnati Reds taking on the Colorado Rockies.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Rockies Game Info

• Cincinnati Reds (18-10) vs. Colorado Rockies (13-16)
• Date: Tuesday, April 28, 2026
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Rockies.TV

Reds vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-205) | COL: (+172)
• Spread: CIN: -1.5 (+104) | COL: +1.5 (-125)
• Total: 9 -- Over: (-105) | Under: (-115)

Reds vs Rockies Probable Starting Pitchers

Probable Pitchers: Chase Burns (Reds) - 2-1, 2.57 ERA vs TBA (Rockies)

The Reds will give the ball to Chase Burns (2-1), while the Rockies' starting pitcher has not yet been announced. Burns' team is 2-3-0 against the spread in his starts this season. When Burns starts a game and his team is the favorite on the moneyline, they have a record of 2-2.

Reds vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (70.2%)

Reds vs Rockies Moneyline

• The moneyline numbers for Reds vs. Rockies reveal Cincinnati as the favorite (-205) and Colorado as the underdog (+172) on the road.

Reds vs Rockies Spread

• The Reds are favored by 1.5 runs at home versus the Rockies. The Reds are +104 to cover the spread, while the Rockies are -125.

Reds vs Rockies Over/Under

• A total of 9 runs has been set for the Reds-Rockies game on April 28, with the over available at -105 and the under at -115.

Bet on Cincinnati Reds vs. Colorado Rockies on FanDuel today!

Reds vs Rockies Betting Trends

• The Reds have been favorites in seven games this season and have come away with the win four times (57.1%) in those contests.
• Oddsmakers have given Cincinnati the best odds of winning it has seen this season, with a -205 moneyline listed for this contest.
• The Reds and their opponents have hit the over in 16 of their 28 games with a total set by oddsmakers this season.
• The Reds are 17-11-0 against the spread in their 28 games with a line set by sportsbooks this season.
• The Rockies have won 13 of the 29 games they were the moneyline underdog this season (44.8%).
• Colorado has a 4-5 record (winning 44.4% of its games) when it has played as a moneyline underdog of +172 or longer.
• The Rockies have combined with opponents to go over the total 10 times this season for a 10-19-0 record against the over/under.
• The Rockies have covered 65.5% of their games this season, going 19-10-0 against the spread.

Reds Player Leaders

• Sal Stewart leads Cincinnati with 30 hits and an OBP of .385 this season. He has a .291 batting average and a slugging percentage of .602.
• Among qualified hitters in baseball, he is 31st in batting average, 21st in on-base percentage, and sixth in slugging.
• Elly De La Cruz leads Cincinnati in slugging percentage (.558) thanks to 14 extra-base hits. He's batting .274 with an on-base percentage of .349.
• Among all qualifying hitters, he is 49th in batting average, 61st in on-base percentage and 13th in slugging percentage.
• De La Cruz enters this game looking to extend his three-game hit streak. During his last five outings he is batting .333 with three home runs, three walks and seven RBIs.
• Matt McLain has collected 21 base hits, an OBP of .339 and a slugging percentage of .327 this season.
• Nathaniel Lowe is batting .256 with a .333 OBP and 10 RBI for Cincinnati this season.
• Lowe has hit safely in five games in a row. In his last five games he is hitting .333 with a double, four home runs, a walk and five RBIs.

Rockies Player Leaders

• Mickey Moniak has five doubles, eight home runs and five walks while hitting .316. He's slugging .684 with an on-base percentage of .353.
• Moniak heads into this matchup on an 11-game hitting streak. During his last 10 outings he is batting .385 with four doubles, three home runs, four walks and six RBIs.
• T.J. Rumfield has four doubles, a triple, three home runs and 11 walks while batting .250. He's slugging .400 with an on-base percentage of .327.
• Including all qualifying players, he is 80th in batting average, 95th in on-base percentage and 92nd in slugging percentage.
• Troy Johnston has a .371 on-base percentage and a .449 slugging percentage, both team-high marks for the Rockies.
• Hunter Goodman leads his team with 25 hits.

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