Rays vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 6:19 p.m.

MLB action on Saturday includes the Tampa Bay Rays taking on the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Rays vs Guardians Game Info

• Tampa Bay Rays (71-70) vs. Cleveland Guardians (70-70)
• Date: Saturday, September 6, 2025
• Time: 7:05 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and CLEG

Rays vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-138) | CLE: (+118)
• Spread: TB: -1.5 (+150) | CLE: +1.5 (-182)
• Total: 8 -- Over: (-112) | Under: (-108)

Rays vs Guardians Probable Starting Pitchers

Probable Pitchers: Shane Baz (Rays) - 9-11, 4.98 ERA vs Tanner Bibee (Guardians) - 9-11, 4.77 ERA

The Rays will call on Shane Baz (9-11) against the Guardians and Tanner Bibee (9-11). Baz and his team are 12-14-0 ATS this season when he starts. Baz's team has a record of 7-5 this season when he starts and they are the favorite on the moneyline. The Guardians have gone 15-11-0 ATS in Bibee's 26 starts with a set spread. The Guardians have been the underdog on the moneyline in 12 of Bibee's starts this season, and they went 4-8 in those games.

Rays vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (65%)

Rays vs Guardians Moneyline

• Cleveland is a +118 underdog on the moneyline, while Tampa Bay is a -138 favorite at home.

Rays vs Guardians Spread

• The Guardians are +1.5 on the spread (-182 to cover), and Tampa Bay is +150 to cover the runline.

Rays vs Guardians Over/Under

• The over/under for Rays-Guardians on Sept. 6 is 8. The over is -112, and the under is -108.

Bet on Tampa Bay Rays vs. Cleveland Guardians on FanDuel today!

Rays vs Guardians Betting Trends

• The Rays have come away with 38 wins in the 64 contests they have been listed as the favorites in this season.
• Tampa Bay has a record of 19-15 in contests when bookmakers favor them by -138 or more on the moneyline.
• The Rays and their opponents have hit the over in 59 of their 136 games with a total set by oddsmakers this season.
• The Rays are 61-75-0 against the spread in their 136 games with a line set by sportsbooks this season.
• The Guardians have put together a 34-46 record in games they were listed as the moneyline underdog (winning 42.5% of those games).
• In games it has played as a moneyline underdog with odds of +118 or longer, Cleveland has a record of 18-18 (50%).
• The Guardians have played in 137 games with a set over/under, and have combined with their opponents to go over the total 62 times (62-69-6).
• The Guardians have covered 51.8% of their games this season, going 71-66-0 ATS.

Rays Player Leaders

• Junior Caminero leads Tampa Bay in total hits (140) this season while batting .263 with 66 extra-base hits. He has an on-base percentage of .304 and a slugging percentage of .541.
• Among qualifying batters, he ranks 63rd in batting average, his on-base percentage ranks 125th, and he is ninth in slugging.
• Caminero will look for his sixth straight game with a hit in this contest. In his last five games he is batting .476 with three doubles, two home runs and nine RBIs.
• Yandy Diaz leads the Rays with an OPS of .827. He has a slash line of .293/.352/.475 this season.
• Among all qualified, he is 13th in batting average, 38th in on-base percentage and 34th in slugging percentage.
• Brandon Lowe is batting .262 with a .486 slugging percentage and 74 RBI this year.
• Chandler Simpson has no home runs, but 22 RBI and a batting average of .290 this season.

Guardians Player Leaders

• Jose Ramirez has put up a team-best OBP (.356), and leads the Guardians in hits (145). He's batting .283 and slugging.
• Including all the qualified hitters in MLB, he ranks 22nd in batting average, 31st in on-base percentage and 18th in slugging percentage.
• Steven Kwan's .380 slugging percentage leads his team. He has a batting average of .274 with an on-base percentage of .331.
• His batting average ranks 37th among all qualified players, his on-base percentage ranks 73rd, and he is 131st in slugging.
• Kyle Manzardo has 14 doubles, two triples, 25 home runs and 43 walks while batting .235.
• Angel Martinez is hitting .225 with 21 doubles, a triple, 10 home runs and 17 walks.

Rays vs Guardians Head to Head

• 9/5/2025: 7-1 CLE (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/4/2025: 4-2 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 8/27/2025: 4-3 CLE (Favorite: Rays, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/26/2025: 3-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/25/2025: 9-0 TB (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/15/2024: 2-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/14/2024: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/13/2024: 3-1 TB (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/12/2024: 5-2 TB (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/14/2024: 2-0 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

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