Twins vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 7:11 p.m.

MLB action on Saturday includes the Minnesota Twins playing the Kansas City Royals.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Royals Game Info

• Minnesota Twins (62-79) vs. Kansas City Royals (72-69)
• Date: Saturday, September 6, 2025
• Time: 7:15 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: FOX

Twins vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-124) | KC: (+106)
• Spread: MIN: -1.5 (+128) | KC: +1.5 (-154)
• Total: 8 -- Over: (-106) | Under: (-114)

Twins vs Royals Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 13-7, 3.08 ERA vs Stephen Kolek (Royals) - 4-5, 3.99 ERA

The Twins will give the ball to Joe Ryan (13-7, 3.08 ERA), who is eyeing win No. 14 on the season, and the Royals will turn to Stephen Kolek (4-5, 3.99 ERA). Ryan and his team have a record of 12-13-0 against the spread when he starts. Ryan's team has been victorious in 55% of the games he's started as the moneyline favorite with a record of 11-9. The Royals have a 10-5-0 ATS record in Kolek's 15 starts with a set spread. The Royals are 3-5 in Kolek's eight starts this season that they were the underdog on the moneyline.

Twins vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.4%)

Twins vs Royals Moneyline

• The Twins vs Royals moneyline has Minnesota as a -124 favorite, while Kansas City is a +106 underdog at home.

Twins vs Royals Spread

• The Twins are at the Royals and are favored by 1.5 runs on the spread. The Twins are +128 to cover the runline, with the Royals being -154.

Twins vs Royals Over/Under

• Twins versus Royals, on Sept. 6, has an over/under of 8, with the over being -106 and the under -114.

Bet on Minnesota Twins vs. Kansas City Royals on FanDuel today!

Twins vs Royals Betting Trends

• The Twins have been chosen as favorites in 81 games this year and have walked away with the win 39 times (48.1%) in those games.
• This season Minnesota has been victorious 25 times in 50 chances when named as a favorite of at least -124 on the moneyline.
• The Twins and their opponents have gone over the total this season in 64 of their 136 opportunities.
• The Twins have posted a record of 66-70-0 against the spread this season.
• The Royals have been the moneyline underdog 78 total times this season. They've finished 36-42 in those games.
• When playing as a moneyline underdog with odds of +106 or longer, Kansas City has a 22-32 record (winning 40.7% of its games).
• The Royals have combined with opponents to hit the over on the total 58 times this season for a 58-79-2 record against the over/under.
• The Royals have put together a 69-70-0 record ATS this season (covering 49.6% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota with 112 hits, batting .271 this season with 53 extra-base hits. He has an on-base percentage of .330 and a slugging percentage of .553.
• Among all qualifying hitters in MLB, his batting average ranks 39th, his on-base percentage ranks 77th, and he is sixth in slugging.
• Trevor Larnach leads Minnesota in slugging percentage (.413) thanks to 37 extra-base hits. He's batting .258 with an on-base percentage of .329.
• His batting average is 81st among qualified players, his on-base percentage 81st, and his slugging percentage 92nd.
• Larnach has picked up a hit in seven straight games. In his last 10 outings he is hitting .432 with two doubles, three walks and five RBIs.
• Brooks Lee has 102 hits this season and has a slash line of .243/.292/.381.
• Ryan Jeffers has 101 hits this season and a team-best OBP of .353.

Royals Player Leaders

• Bobby Witt Jr. has totaled 160 hits with a .503 slugging percentage, both team-best numbers for the Royals. He's batting .294 and with an on-base percentage of .352.
• He ranks 11th in batting average, 37th in on-base percentage and 17th in slugging percentage among all qualifying hitters in the big leagues.
• Maikel Garcia has a .357 on-base percentage to pace his team. He has a batting average of .294 while slugging .472.
• He ranks 11th in batting average, 26th in on-base percentage and 38th in slugging percentage in the big leagues.
• Vinnie Pasquantino is hitting .260 with 23 doubles, a triple, 29 home runs and 43 walks.
• Salvador Perez is hitting .238 with 33 doubles, 24 home runs and 23 walks.

Twins vs Royals Head to Head

• 9/5/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/10/2025: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/9/2025: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2025: 9-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/25/2025: 2-1 KC (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/24/2025: 5-4 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/23/2025: 3-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2025: 3-2 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/9/2025: 4-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/8/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

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