Phillies vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 28

Odds updated as of 2:12 p.m.

The MLB schedule on Sunday includes the Philadelphia Phillies taking on the Minnesota Twins.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Twins Game Info

• Philadelphia Phillies (95-66) vs. Minnesota Twins (70-91)
• Date: Sunday, September 28, 2025
• Time: 3:05 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and MNNT

Phillies vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-250) | MIN: (+205)
• Spread: PHI: -1.5 (-120) | MIN: +1.5 (-100)
• Total: 8 -- Over: (-118) | Under: (-104)

Phillies vs Twins Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 13-5, 2.57 ERA vs Simeon Woods Richardson (Twins) - 7-4, 4.27 ERA

The Phillies will give the nod to Cristopher Sanchez (13-5, 2.57 ERA), who is eyeing win No. 14 on the season, and the Twins will turn to Simeon Woods Richardson (7-4, 4.27 ERA). Sanchez's team is 18-13-0 against the spread this season in his starts. Sanchez's team is 20-7 this season when he starts and they are the moneyline favorite. The Twins have a 12-8-0 ATS record in Woods Richardson's 20 starts that had a set spread. The Twins have been the moneyline underdog in nine of Woods Richardson's starts this season, and they went 6-3 in those matchups.

Phillies vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (68.1%)

Phillies vs Twins Moneyline

• Looking at the moneyline for Twins-Phillies, Minnesota is the underdog at +205, and Philadelphia is -250 playing at home.

Phillies vs Twins Spread

• The Phillies are 1.5-run home favorites on the runline against the Twins. The Phillies are -120 to cover, and the Twins are -100.

Phillies vs Twins Over/Under

• Phillies versus Twins, on Sept. 28, has an over/under of 8, with the over being -118 and the under -104.

Bet on Philadelphia Phillies vs. Minnesota Twins on FanDuel today!

Phillies vs Twins Betting Trends

• The Phillies have been favorites in 121 games this season and have come away with the win 78 times (64.5%) in those contests.
• Philadelphia has a record of 10-1 in contests when oddsmakers favor them by -250 or more on the moneyline.
• Contests with the Phillies have gone over the total set by bookmakers in 65 of 154 chances this season.
• The Phillies are 79-75-0 against the spread in their 154 games with a line set by sportsbooks this season.
• The Twins have a 26-40 record in games they were listed as the moneyline underdog (winning 39.4% of those games).
• Minnesota has played as a moneyline underdog of +205 or longer in only one game this season, which it lost.
• The Twins have played in 156 games with a set over/under, and have combined with opponents to go over the total 72 times (72-77-7).
• The Twins have covered 48.1% of their games this season, going 75-81-0 against the spread.

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 145 hits and an OBP of .365 this season. He has a .241 batting average and a slugging percentage of .566.
• Among all qualifying hitters in the majors, he ranks 110th in batting average, 14th in on-base percentage, and fourth in slugging.
• Bryce Harper is hitting .264 with 32 doubles, 27 home runs and 70 walks. He's slugging .491 with an on-base percentage of .359.
• He is 54th in batting average, 20th in on-base percentage and 21st in slugging in the majors.
• Harper heads into this game looking to extend his four-game hit streak. During his last five outings he is batting .211 with two walks.
• Bryson Stott has 127 hits this season and has a slash line of .256/.328/.391.
• Nick Castellanos is batting .252 with a .296 OBP and 71 RBI for Philadelphia this season.

Twins Player Leaders

• Byron Buxton has 129 hits with a .327 on-base percentage and a .551 slugging percentage, all club-highs for the Twins. He's batting .264.
• He is 54th in batting average, 81st in on-base percentage and fifth in slugging percentage among all qualified hitters in the majors.
• Trevor Larnach is hitting .249 with 23 doubles, a triple, 17 home runs and 53 walks. He's slugging .400 with an on-base percentage of .322.
• He is 94th in batting average, 93rd in on-base percentage and 104th in slugging percentage in the majors.
• Brooks Lee is hitting .236 with 15 doubles, a triple, 16 home runs and 30 walks.
• Ryan Jeffers has 25 doubles, nine home runs and 49 walks while batting .261.

Phillies vs Twins Head to Head

• 9/27/2025: 5-0 MIN (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/26/2025: 3-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/24/2024: 5-4 MIN (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/23/2024: 3-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/13/2023: 3-0 MIN (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2023: 13-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)

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