Phillies vs Mets Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 6:18 p.m.

The Philadelphia Phillies are among the MLB squads busy on Wednesday, up against the New York Mets.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Mets Game Info

• Philadelphia Phillies (85-60) vs. New York Mets (76-69)
• Date: Wednesday, September 10, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and SNY

Phillies vs Mets Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-162) | NYM: (+136)
• Spread: PHI: -1.5 (+132) | NYM: +1.5 (-160)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Phillies vs Mets Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 12-5, 2.60 ERA vs Clay Holmes (Mets) - 11-7, 3.61 ERA

This contest's pitching matchup is set, as the Phillies will send Cristopher Sanchez (12-5) to the mound, while Clay Holmes (11-7) will take the ball for the Mets. Sanchez and his team are 16-12-0 ATS this season when he starts. When Sanchez starts a game and his team is the favorite on the moneyline, they have a record of 19-6. When Holmes starts, the Mets are 11-14-0 against the spread. The Mets have been the moneyline underdog in five of Holmes' starts this season, and they went 2-3 in those games.

Phillies vs Mets Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (60.5%)

Phillies vs Mets Moneyline

• Looking at the moneyline for Phillies-Mets, Philadelphia is the favorite at -162, and New York is +136 playing on the road.

Phillies vs Mets Spread

• The Phillies are hosting the Mets and are favored by 1.5 runs on the spread. The Phillies are +132 to cover the runline, with the Mets being -160.

Phillies vs Mets Over/Under

• The Phillies-Mets game on Sept. 10 has been given an over/under of 7.5 runs. The over is set at -112 and the under at -108.

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Phillies vs Mets Betting Trends

• The Phillies have been chosen as favorites in 110 games this year and have walked away with the win 71 times (64.5%) in those games.
• This season Philadelphia has been victorious 41 times in 56 chances when named as a favorite of at least -162 on the moneyline.
• The Phillies and their opponents have hit the over in 54 of their 138 games with a total set by oddsmakers this season.
• The Phillies have an against the spread record of 71-67-0 in 138 games with a line this season.
• The Mets have put together a 15-23 record in games they were the underdog on the moneyline (winning 39.5% of those games).
• New York has played in four games as a moneyline underdog with odds of +136 or longer without earning a win.
• The Mets have played in 138 games with an over/under set, and have combined with their opponents to go over the total 63 times (63-67-8).
• The Mets have a 65-73-0 record ATS this season.

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 130 hits and an OBP of .364 this season. He has a .240 batting average and a slugging percentage of .562.
• He is 113th in batting average, 17th in on-base percentage, and fifth in slugging among qualified hitters in MLB.
• Bryce Harper is hitting .263 with 30 doubles, 24 home runs and 58 walks, while slugging .491 with an on-base percentage of .352.
• Among all qualifying hitters, he is 60th in batting average, 34th in on-base percentage and 24th in slugging percentage.
• Bryson Stott has 113 hits this season and has a slash line of .255/.326/.381.
• Stott has recorded at least one base hit in two games in a row. During his last five outings he is batting .412 with a double, a home run, two walks and five RBIs.
• Nick Castellanos is batting .253 with a .296 OBP and 65 RBI for Philadelphia this season.
• Castellanos takes a four-game hitting streak into this game. During his last five outings he is hitting .294 with a double, a triple, two walks and four RBIs.

Mets Player Leaders

• Juan Soto has 133 hits with a .399 on-base percentage, leading the Mets in both statistics. He's batting .261 and slugging .522.
• Including all the qualified hitters in the big leagues, his batting average puts him 70th, his on-base percentage ranks second, and he is 13th in slugging.
• Francisco Lindor paces his team with a .454 slugging percentage. He has a batting average of .264 with an on-base percentage of .339.
• Including all qualifying hitters, he ranks 57th in batting average, 52nd in on-base percentage and 56th in slugging percentage.
• Pete Alonso is batting .269 with 37 doubles, a triple, 33 home runs and 56 walks.
• Brandon Nimmo has 27 doubles, 22 home runs and 48 walks while batting .263.

Phillies vs Mets Head to Head

• 9/9/2025: 9-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 9/8/2025: 1-0 PHI (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/27/2025: 6-0 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/26/2025: 6-5 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/25/2025: 13-3 NYM (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/22/2025: 7-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/21/2025: 11-4 NYM (Favorite: Mets, Spread: -1.5, Total: 10.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/20/2025: 10-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 4/23/2025: 4-3 NYM (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/22/2025: 5-1 NYM (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

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