Marlins vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 6:12 p.m.

The Wednesday slate in MLB includes a matchup between the Miami Marlins and the Washington Nationals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Marlins vs Nationals Game Info

• Miami Marlins (66-79) vs. Washington Nationals (60-84)
• Date: Wednesday, September 10, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and MASN2

Marlins vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-156) | WSH: (+132)
• Spread: MIA: -1.5 (+134) | WSH: +1.5 (-162)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Marlins vs Nationals Probable Starting Pitchers

Probable Pitchers: Eury Pérez (Marlins) - 6-5, 4.66 ERA vs Jake Irvin (Nationals) - 8-11, 5.71 ERA

The Marlins will look to Eury Perez (6-5) against the Nationals and Jake Irvin (8-11). Perez and his team are 8-6-0 ATS this season when he starts. When Perez starts a game and his team is the favorite on the moneyline, they have a record of 1-4. The Nationals are 15-13-0 against the spread when Irvin starts. The Nationals have been the underdog on the moneyline in 27 of Irvin's starts this season, and they went 13-14 in those games.

Marlins vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (61.3%)

Marlins vs Nationals Moneyline

• Looking at the moneyline for Marlins-Nationals, Miami is the favorite at -156, and Washington is +132 playing on the road.

Marlins vs Nationals Spread

• The Marlins are hosting the Nationals and are favored by 1.5 runs on the spread. The Marlins are +134 to cover the runline, with the Nationals being -162.

Marlins vs Nationals Over/Under

• A total of 8.5 runs has been set for the Marlins-Nationals contest on Sept. 10, with the over available at -115 and the under at -105.

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Marlins vs Nationals Betting Trends

• The Marlins have been favorites in 23 games this season and have come away with the win eight times (34.8%) in those contests.
• Miami has been listed as a favorite of -156 or more on two occasions this season and lost both games.
• The Marlins and their opponents have gone over in 69 of their 141 games with a total set by sportsbooks this season.
• In 141 games with a line this season, the Marlins have a mark of 79-62-0 against the spread.
• The Nationals have won 44.4% of the games this season they were the underdog on the moneyline (52-65).
• Washington has gone 27-37 when it has played as a moneyline underdog with odds of +132 or longer (42.2%).
• The Nationals have had an over/under set by oddsmakers 138 times, and have combined with opponents to go over the total in 74 of those games (74-57-7).
• The Nationals are 70-68-0 against the spread this season.

Marlins Player Leaders

• Otto Lopez is hitting .249 with 18 doubles, 14 home runs and 44 walks. He has an on-base percentage of .315 while slugging .376.
• Among qualified hitters in MLB, he is 93rd in batting average, 104th in on-base percentage, and 129th in slugging.
• Lopez hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .353 with two home runs and four RBIs.
• Xavier Edwards has an OPS of .686, fueled by an OBP of .337 and a team-best slugging percentage of .348 this season. He's batting .279.
• His batting average is 25th among qualified players, his on-base percentage 54th, and his slugging percentage 141st.
• Edwards has picked up at least one hit in two straight games. In his last five games he is batting .143 with three walks and two RBIs.
• Agustin Ramirez has 107 hits this season and has a slash line of .226/.283/.410.
• Eric Wagaman has been key for Miami with 103 hits, an OBP of .289 plus a slugging percentage of .372.

Nationals Player Leaders

• C.J. Abrams is hitting .268 with 33 doubles, five triples, 17 home runs and 35 walks. He's slugging .451 with an on-base percentage of .331.
• He ranks 47th in batting average, 71st in on-base percentage and 60th in slugging percentage among all qualifying batters in the big leagues.
• Abrams heads into this matchup on a six-game hitting streak. In his last 10 games he is batting .289 with six doubles and three walks.
• James Wood has 140 hits with a .357 OBP while slugging .473. Those stats all lead his team. He also has a batting average of .260.
• Including all qualified players, he ranks 73rd in batting average, 26th in on-base percentage and 34th in slugging percentage.
• Luis Garcia is batting .260 with 27 doubles, a triple, 13 home runs and 26 walks.
• Josh Bell is hitting .232 with 13 doubles, a triple, 20 home runs and 54 walks.

Marlins vs Nationals Head to Head

• 9/9/2025: 7-5 WSH (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/8/2025: 15-7 WSH (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/3/2025: 10-5 WSH (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/2/2025: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/1/2025: 2-0 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/15/2025: 3-1 MIA (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/14/2025: 4-3 MIA (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/13/2025: 11-9 MIA (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/13/2025: 11-4 MIA (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/12/2025: 7-6 MIA (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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