Phillies vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 3:12 p.m.

The Philadelphia Phillies are among the MLB teams playing on Saturday, versus the Miami Marlins.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Phillies vs Marlins Game Info

• Philadelphia Phillies (82-59) vs. Miami Marlins (65-76)
• Date: Saturday, September 6, 2025
• Time: 4:10 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and NBCS-PH

Phillies vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-154) | MIA: (+130)
• Spread: PHI: -1.5 (+112) | MIA: +1.5 (-134)
• Total: 8 -- Over: (-106) | Under: (-114)

Phillies vs Marlins Probable Starting Pitchers

Probable Pitchers: Jesús Luzardo (Phillies) - 12-6, 4.05 ERA vs Sandy Alcantara (Marlins) - 8-11, 5.66 ERA

The Phillies will give the ball to Jesus Luzardo (12-6, 4.05 ERA), who is eyeing win No. 13 on the season, and the Marlins will turn to Sandy Alcantara (8-11, 5.66 ERA). When Luzardo starts, his team is 12-15-0 against the spread this season. Luzardo's team has won 59.1% of his starts when they are favored on the moneyline (13-9). The Marlins are 13-14-0 against the spread when Alcantara starts. The Marlins have a 10-11 record in Alcantara's 21 starts this season when they were the underdog on the moneyline.

Phillies vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (60.6%)

Phillies vs Marlins Moneyline

• Looking at the moneyline for Phillies-Marlins, Philadelphia is the favorite at -154, and Miami is +130 playing at home.

Phillies vs Marlins Spread

• The Marlins are +1.5 on the run line against the Phillies. The Marlins are -134 to cover, and the Phillies are +112.

Phillies vs Marlins Over/Under

• Phillies versus Marlins, on Sept. 6, has an over/under of 8, with the over being -106 and the under -114.

Bet on Philadelphia Phillies vs. Miami Marlins on FanDuel today!

Phillies vs Marlins Betting Trends

• The Phillies have been favorites in 107 games this season and have come away with the win 69 times (64.5%) in those contests.
• This year Philadelphia has won 46 of 65 games when listed as at least -154 on the moneyline.
• The Phillies and their opponents have hit the over in 53 of their 134 games with a total set by oddsmakers this season.
• The Phillies are 68-66-0 against the spread in their 134 games with a line set by sportsbooks this season.
• The Marlins have won 46.5% of the games this season they were the moneyline underdog (53-61).
• In games it has played as a moneyline underdog with odds of +130 or longer, Miami has a 26-28 record (winning 48.1% of its games).
• The Marlins have played in 137 games with an over/under set, and have combined with their opponents to go over the total 67 times (67-70-0).
• The Marlins have collected a 78-59-0 record ATS this season.

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia in OBP (.366) and total hits (128) this season. He's batting .243 batting average while slugging .568.
• Among all qualifying hitters, he is 113th in batting average, his on-base percentage ranks 16th, and he is fourth in slugging.
• Trea Turner has an OPS of .812, fueled by an OBP of .357 and a team-best slugging percentage of .455 this season. He's batting .305.
• His batting average is fourth among qualified players, his on-base percentage 26th, and his slugging percentage 54th.
• Turner enters this game looking to extend his six-game hit streak. In his last 10 games he is batting .386 with three doubles, a triple, two walks and seven RBIs.
• Bryce Harper has 114 hits this season and has a slash line of .265/.356/.492.
• Bryson Stott has 10 home runs, 59 RBI and a batting average of .251 this season.
• Stott heads into this game on a seven-game hitting streak. During his last 10 games he is hitting .290 with two doubles, a home run, four walks and six RBIs.

Marlins Player Leaders

• Otto Lopez has 18 doubles, 12 home runs and 44 walks while hitting .246. He's slugging .363 with an on-base percentage of .314.
• He ranks 105th in batting average, 107th in on-base percentage and 142nd in slugging percentage among all qualified hitters in the big leagues.
• Lopez hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .267 with three walks and an RBI.
• Xavier Edwards' .352 slugging percentage leads his team. He has a batting average of .281 with an on-base percentage of .338.
• He is currently 23rd in batting average, 58th in on-base percentage and 145th in slugging percentage among all qualifying hitters.
• Agustin Ramirez has 28 doubles, a triple, 19 home runs and 30 walks while hitting .228.
• Eric Wagaman has 24 doubles, three triples, nine home runs and 31 walks while batting .237.

Phillies vs Marlins Head to Head

• 9/5/2025: 9-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 6/19/2025: 2-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/18/2025: 4-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 6/16/2025: 5-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/20/2025: 7-5 MIA (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 4/19/2025: 11-10 PHI (Favorite: Phillies, Spread: -1.5, Total: 10.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 4/18/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/8/2024: 10-1 MIA (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/7/2024: 9-5 MIA (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 9/6/2024: 16-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -290, Underdog Moneyline: +235)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!