Padres vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 3

Odds updated as of 11:14 p.m.

The MLB's Sunday slate includes the San Diego Padres taking on the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this game.

Padres vs White Sox Game Info

• San Diego Padres (19-12) vs. Chicago White Sox (15-17)
• Date: Sunday, May 3, 2026
• Time: 4:10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and CHSN

Padres vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-184) | CHW: (+154)
• Spread: SD: -1.5 (+116) | CHW: +1.5 (-140)
• Total: 8 -- Over: (-105) | Under: (-115)

Padres vs White Sox Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 3-0, 2.94 ERA vs Anthony Kay (White Sox) - 1-1, 6.12 ERA

The Padres will give the ball to Randy Vasquez (3-0, 2.94 ERA), who is eyeing win No. 4 on the season, and the White Sox will counter with Anthony Kay (1-1, 6.12 ERA). Vasquez and his team are 5-1-0 ATS this season when he starts. Vasquez and his team have won each of the three games he's started as the moneyline favorite. The White Sox are 1-2-0 ATS in Kay's three starts that had a set spread. The White Sox have been the moneyline underdog in three of Kay's starts this season, and they went 1-2 in those games.

Padres vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (63.7%)

Padres vs White Sox Moneyline

• San Diego is a -184 favorite on the moneyline, while Chicago is a +154 underdog on the road.

Padres vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Padres. The White Sox are -140 to cover the spread, and the Padres are +116.

Padres vs White Sox Over/Under

• The over/under for the Padres versus White Sox game on May 3 has been set at 8, with -105 odds on the over and -115 odds on the under.

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Padres vs White Sox Betting Trends

• The Padres have been victorious in 10, or 62.5%, of the 16 contests they have been chosen as favorites in this season.
• San Diego has been listed as a favorite of -184 or more on two occasions this season and won both games.
• The Padres and their opponents have gone over in 15 of their 31 games with a total set by sportsbooks this season.
• In 31 games with a line this season, the Padres have a mark of 19-12-0 against the spread.
• The White Sox are 12-15 in games they were listed as the moneyline underdog (winning 44.4% of those games).
• Chicago is 1-2 (winning only 33.3% of its games) when it has played as a moneyline underdog of +154 or longer.
• The White Sox have combined with opponents to go over the total 17 times this season for a 17-13-0 record against the over/under.
• The White Sox have a 16-14-0 record ATS this season (covering 53.3% of the time).

Padres Player Leaders

• Xander Bogaerts leads San Diego in OBP (.349) this season, fueled by 30 hits. He has a .268 batting average and a slugging percentage of .420.
• Among qualifying hitters in MLB, his batting average ranks 57th, his on-base percentage ranks 68th, and he is 81st in slugging.
• Manny Machado is hitting .225 with four doubles, four home runs and 18 walks, while slugging .382 with an on-base percentage of .336.
• He is 129th in batting average, 83rd in on-base percentage and 111th in slugging among qualifying batters.
• Jackson Merrill has collected 23 base hits, an OBP of .270 and a slugging percentage of .330 this season.
• Ramon Laureano has 27 hits, which is best among San Diego hitters this season, while batting .243 with 10 extra-base hits.

White Sox Player Leaders

• Munetaka Murakami has an on-base percentage of .383 and has 27 hits, both team-best numbers for the White Sox. He's batting .239 and slugging .584.
• Including all qualified hitters, he is 107th in batting average, while his on-base percentage ranks 29th and he is ninth in slugging.
• Miguel Vargas is batting .214 with four doubles, a triple, six home runs and 24 walks. He's slugging .429 with an on-base percentage of .360.
• Including all qualifying hitters, his batting average places him 138th, his on-base percentage ranks 56th, and he is 70th in slugging.
• Colson Montgomery is hitting .237 with five doubles, nine home runs and 11 walks.
• Chase Meidroth is slugging .345 to pace his team.

Padres vs White Sox Head to Head

• 5/1/2026: 8-2 CHW (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/21/2025: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 9/20/2025: 7-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 9/19/2025: 4-3 CHW (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/22/2024: 4-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -350, Underdog Moneyline: +280)
• 9/21/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 9/20/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -295, Underdog Moneyline: +240)
• 10/1/2023: 2-1 SD (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/30/2023: 6-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/29/2023: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)

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