Padres vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 11

Odds updated as of 9:11 p.m.

The San Diego Padres will face the Colorado Rockies in MLB action on Thursday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this game.

Padres vs Rockies Game Info

• San Diego Padres (79-67) vs. Colorado Rockies (40-106)
• Date: Thursday, September 11, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and COLR

Padres vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-270) | COL: (+220)
• Spread: SD: -1.5 (-130) | COL: +1.5 (+108)
• Total: 8.5 -- Over: (-118) | Under: (-104)

Padres vs Rockies Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 4-6, 3.91 ERA vs McCade Brown (Rockies) - 0-3, 12.54 ERA

This contest's pitching matchup is set, as the Padres will send Randy Vasquez (4-6) to the mound, while McCade Brown (0-3) will answer the bell for the Rockies. Vasquez's team is 14-8-0 against the spread this season in his starts. Vasquez's team has won 85.7% of his starts when they are favored on the moneyline (6-1). The Rockies have a 1-2-0 record against the spread in Brown's starts. The Rockies were the moneyline underdog for three Brown starts this season -- they lost every time.

Padres vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (67.8%)

Padres vs Rockies Moneyline

• The moneyline numbers for Padres vs. Rockies reveal San Diego as the favorite (-270) and Colorado as the underdog (+220) on the road.

Padres vs Rockies Spread

• The Padres are 1.5-run home favorites on the runline against the Rockies. The Padres are -130 to cover, and the Rockies are +108.

Padres vs Rockies Over/Under

• The over/under for Padres-Rockies on Sept. 11 is 8.5. The over is -118, and the under is -104.

Bet on San Diego Padres vs. Colorado Rockies on FanDuel today!

Padres vs Rockies Betting Trends

• The Padres have been victorious in 46, or 59%, of the 78 contests they have been chosen as favorites in this season.
• San Diego has played as a favorite of -270 or more just one time this year and came away with a loss in that game.
• The Padres and their opponents have gone over in 62 of their 144 games with a total set by sportsbooks this season.
• The Padres are 77-67-0 against the spread in their 144 games that had a posted line this season.
• The Rockies have gone 36-102 in games they were listed as the moneyline underdog (winning 26.1% of those games).
• When it has played as a moneyline underdog with odds of +220 or longer, Colorado has gone 8-38 (17.4%).
• The Rockies have combined with opponents to go over the total 61 times this season for a 61-76-5 record against the over/under.
• The Rockies have put together a 57-85-0 record ATS this season (covering 40.1% of the time).

Padres Player Leaders

• Fernando Tatis Jr. is hitting .262 with 27 doubles, two triples, 21 home runs and 84 walks. He has an on-base percentage of .366 while slugging .435.
• Among all qualifying hitters in baseball, his batting average ranks 66th, his on-base percentage ranks 15th, and he is 77th in slugging.
• Manny Machado is batting .274 with 33 doubles, 23 home runs and 51 walks. He's slugging .455 with an on-base percentage of .335.
• Among qualified hitters, his batting average ranks him 35th, his on-base percentage 60th, and his slugging percentage 55th.
• Luis Arraez leads San Diego in slugging percentage (.385) powered by 40 extra-base hits.
• Ramon Laureano is batting .295 with a .357 OBP and 71 RBI for San Diego this season.

Rockies Player Leaders

• Hunter Goodman has accumulated 135 hits with a .539 slugging percentage, both team-high numbers for the Rockies. He's batting .282 and with an on-base percentage of .328.
• Including all the qualified hitters in MLB, his batting average puts him 20th, his on-base percentage is 77th, and he is ninth in slugging.
• Mickey Moniak is hitting .260 with 17 doubles, eight triples, 19 home runs and 21 walks. He's slugging .494 with an on-base percentage of .299.
• Jordan Beck a has .330 on-base percentage to pace the Rockies.
• Brenton Doyle is hitting .242 with 20 doubles, two triples, 14 home runs and 29 walks.

Padres vs Rockies Head to Head

• 9/7/2025: 8-1 SD (Favorite: Padres, Spread: -1.5, Total: 11, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/6/2025: 10-8 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/5/2025: 3-0 COL (Favorite: Padres, Spread: -1.5, Total: 10.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/11/2025: 9-3 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/10/2025: 21-0 SD (Favorite: Padres, Spread: -1.5, Total: 12, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/9/2025: 13-9 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 4/13/2025: 6-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/12/2025: 2-0 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/11/2025: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/18/2024: 3-2 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -196, Underdog Moneyline: +164)

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