Guardians vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 11

Odds updated as of 7:17 p.m.

In MLB action on Thursday, the Cleveland Guardians face the Kansas City Royals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Guardians vs Royals Game Info

• Cleveland Guardians (74-71) vs. Kansas City Royals (74-72)
• Date: Thursday, September 11, 2025
• Time: 7:15 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: FOX

Guardians vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-136) | KC: (+116)
• Spread: CLE: -1.5 (+158) | KC: +1.5 (-192)
• Total: 7.5 -- Over: (-108) | Under: (-112)

Guardians vs Royals Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 10-5, 3.17 ERA vs Stephen Kolek (Royals) - 5-5, 3.88 ERA

The probable pitchers are Gavin Williams (10-5) for the Guardians and Stephen Kolek (5-5) for the Royals. When Williams starts, his team is 13-15-0 against the spread this season. Williams' team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 6-4. When Kolek starts, the Royals have gone 11-5-0 against the spread. The Royals are 4-5 in Kolek's nine starts this season that they were the moneyline underdog.

Guardians vs Royals Moneyline

• Kansas City is a +116 underdog on the moneyline, while Cleveland is a -136 favorite at home.

Guardians vs Royals Spread

• The Guardians are hosting the Royals and are favored by 1.5 runs (+158 to cover) on the runline. Kansas City is -192 to cover.

Guardians vs Royals Over/Under

• The Guardians-Royals contest on Sept. 11 has been given an over/under of 7.5 runs. The over is set at -108 and the under at -112.

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Guardians vs Royals Betting Trends

• The Guardians have been victorious in 36, or 62.1%, of the 58 contests they have been chosen as favorites in this season.
• Cleveland has a record of 14-5 in contests when sportsbooks favor them by -136 or more on the moneyline.
• The Guardians and their opponents have gone over in 63 of their 142 games with a total set by sportsbooks this season.
• The Guardians have an against the spread record of 76-66-0 in 142 games with a line this season.
• The Royals have won 46.3% of the games this season they were the underdog on the moneyline (38-44).
• When it has played as a moneyline underdog with odds of +116 or longer, Kansas City has an 18-20 record (winning 47.4% of its games).
• The Royals have played in 144 games with an over/under set, and have combined with their opponents to go over the total 60 times (60-82-2).
• The Royals have a 70-74-0 record ATS this season (covering 48.6% of the time).

Guardians Player Leaders

• Jose Ramirez has 152 hits and an OBP of .361, both of which are best among Cleveland hitters this season. He has a .287 batting average and a slugging percentage of .511.
• Among the qualifying batters in MLB, his batting average ranks 17th, his on-base percentage ranks 20th, and he is 15th in slugging.
• Ramirez will look for his eighth straight game with a hit in this contest. In his last 10 games he is hitting .342 with four doubles, a triple, two home runs, three walks and eight RBIs.
• Steven Kwan has hit 10 homers this season while driving in 48 runs. He's batting .276 this season and slugging .379 with an on-base percentage of .335.
• He ranks 30th in batting average, 60th in on-base percentage and 125th in slugging in MLB.
• Kyle Manzardo has 98 hits this season and has a slash line of .240/.325/.477.
• Manzardo has logged a hit or more in three straight games. In his last five games he is hitting .400 with a double, two home runs, four walks and five RBIs.
• Angel Martinez is batting .225 with a .264 OBP and 41 RBI for Cleveland this season.

Royals Player Leaders

• Bobby Witt Jr. has put up a slugging percentage of .501 and has 163 hits, both team-best figures for the Royals. He's batting .295 and with an on-base percentage of .352.
• Including all the qualifying players in the majors, his batting average puts him eighth, his on-base percentage is 34th, and he is 20th in slugging.
• Maikel Garcia's .355 OBP leads his team. He has a batting average of .292 while slugging .467.
• He ranks 11th in batting average, 30th in on-base percentage and 42nd in slugging percentage in the big leagues.
• Vinnie Pasquantino has 24 doubles, a triple, 29 home runs and 44 walks while batting .262.
• Salvador Perez is hitting .235 with 34 doubles, 25 home runs and 23 walks.

Guardians vs Royals Head to Head

• 9/10/2025: 4-3 KC (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/9/2025: 2-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/8/2025: 10-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/27/2025: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/26/2025: 6-4 CLE (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/26/2025: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/13/2025: 4-2 KC (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/12/2025: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/11/2025: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2025: 6-2 CLE (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)

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