Orioles vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 6:12 p.m.

The MLB slate on Wednesday includes the Baltimore Orioles taking on the Tampa Bay Rays.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Orioles vs Rays Game Info

• Baltimore Orioles (74-83) vs. Tampa Bay Rays (76-81)
• Date: Wednesday, September 24, 2025
• Time: 6:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: Fox Sports 1, MASN2, and FDSSUN

Orioles vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-124) | TB: (+106)
• Spread: BAL: -1.5 (+162) | TB: +1.5 (-196)
• Total: 8 -- Over: (-102) | Under: (-120)

Orioles vs Rays Probable Starting Pitchers

Probable Pitchers: Tyler Wells (Orioles) - 2-0, 2.04 ERA vs Shane Baz (Rays) - 10-12, 4.99 ERA

The Orioles will give the nod to Tyler Wells (2-0, 2.04 ERA), who is eyeing win No. 3 on the season, and the Rays will turn to Shane Baz (10-12, 4.99 ERA). Wells and his team have covered in each of the three games he's started with a spread this season. Wells' team won his only start as a favorite this season. When Baz starts, the Rays are 13-16-0 against the spread. The Rays have a 6-7 record in Baz's 13 starts this season when they were the moneyline underdog.

Orioles vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (52.1%)

Orioles vs Rays Moneyline

• Baltimore is a -124 favorite on the moneyline, while Tampa Bay is a +106 underdog on the road.

Orioles vs Rays Spread

• The Rays are +1.5 on the spread (-196 to cover), and Baltimore is +162 to cover the runline.

Orioles vs Rays Over/Under

• A combined run total of 8 has been set for Orioles-Rays on Sept. 24, with the over at -102 and the under at -120.

Bet on Baltimore Orioles vs. Tampa Bay Rays on FanDuel today!

Orioles vs Rays Betting Trends

• The Orioles have won in 31, or 50%, of the 62 contests they have been named as odds-on favorites in this year.
• This year Baltimore has won 22 of 41 games when listed as at least -124 on the moneyline.
• The Orioles and their opponents have hit the over in 63 of their 154 games with a total set by oddsmakers this season.
• The Orioles are 74-80-0 against the spread in their 154 games that had a posted line this season.
• The Rays have a 31-44 record in games they were the underdog on the moneyline (winning 41.3% of those games).
• Tampa Bay has a 21-25 record (winning 45.7% of its games) when playing as a moneyline underdog of +106 or longer.
• The Rays have played in 152 games with a set over/under, and have combined with their opponents to go over the total 67 times (67-77-8).
• The Rays have covered 44.1% of their games this season, going 67-85-0 ATS.

Orioles Player Leaders

• Gunnar Henderson leads Baltimore with 153 hits and an OBP of .349, plus a team-best slugging percentage of .437. He's batting .274.
• He is 32nd in batting average, 40th in on-base percentage, and 68th in slugging among qualifying batters in baseball.
• Jackson Holliday is hitting .245 with 21 doubles, three triples, 17 home runs and 54 walks. He's slugging .381 with an on-base percentage of .316.
• Among qualifiers, he is 100th in batting average, 99th in on-base percentage and 124th in slugging percentage.
• Jordan Westburg is batting .264 with a .450 slugging percentage and 35 RBI this year.
• Adley Rutschman has nine home runs, 29 RBI and a batting average of .224 this season.

Rays Player Leaders

• Junior Caminero has put up 151 hits, a team-best for the Rays. He's batting .259 and slugging .533 with an on-base percentage of .304.
• Including all qualified hitters in the majors, he ranks 65th in batting average, 117th in on-base percentage and eighth in slugging percentage.
• Yandy Diaz has a .366 on-base percentage while slugging .485. Both lead his team. He has a batting average of .301.
• He is currently eighth in batting average, 14th in on-base percentage and 24th in slugging percentage among all qualified hitters.
• Brandon Lowe is hitting .257 with 18 doubles, 30 home runs and 37 walks.
• Chandler Simpson is batting .298 with 14 doubles, three triples and 20 walks.

Orioles vs Rays Head to Head

• 9/23/2025: 6-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/20/2025: 5-3 BAL (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/19/2025: 4-3 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/18/2025: 11-1 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/29/2025: 5-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/28/2025: 11-3 TB (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/27/2025: 22-8 BAL (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/19/2025: 4-1 BAL (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/18/2025: 12-8 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/17/2025: 5-1 BAL (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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