Orioles vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 2:12 a.m.

In MLB action on Wednesday, the Baltimore Orioles play the Tampa Bay Rays.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this game.

Orioles vs Rays Game Info

• Baltimore Orioles (74-83) vs. Tampa Bay Rays (76-81)
• Date: Wednesday, September 24, 2025
• Time: 6:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: Fox Sports 1, MASN2, and FDSSUN

Orioles vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-116) | TB: (-102)
• Spread: BAL: +1.5 (-192) | TB: -1.5 (+155)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Orioles vs Rays Probable Starting Pitchers

Probable Pitchers: Tyler Wells (Orioles) - 2-0, 2.04 ERA vs Shane Baz (Rays) - 10-12, 4.99 ERA

The Orioles will give the ball to Tyler Wells (2-0, 2.04 ERA), who is eyeing win No. 3 on the season, and the Rays will turn to Shane Baz (10-12, 4.99 ERA). Wells' team has covered the spread in each of the three opportunities this season. Wells' team won his only start as a favorite this season. The Rays are 13-16-0 against the spread when Baz starts. The Rays are 6-7 in Baz's 13 starts this season that they were the underdog on the moneyline.

Orioles vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (51.9%)

Orioles vs Rays Moneyline

• Baltimore is the favorite, -116 on the moneyline, while Tampa Bay is a -102 underdog on the road.

Orioles vs Rays Spread

• The Rays are 1.5-run favorites against the spread for this matchup with the Orioles. The Rays are +155 to cover, while the Orioles are -192 to cover as a 1.5-run underdog on the runline.

Orioles vs Rays Over/Under

• The Orioles-Rays contest on Sept. 24 has been given an over/under of 8.5 runs. The over is set at -112 and the under at -108.

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Orioles vs Rays Betting Trends

• The Orioles have been chosen as favorites in 62 games this year and have walked away with the win 31 times (50%) in those games.
• This season Baltimore has come away with a win 28 times in 55 chances when named as a favorite of at least -116 on the moneyline.
• The Orioles and their opponents have gone over the total this season in 63 of their 154 opportunities.
• The Orioles are 74-80-0 against the spread in their 154 games with a line set by sportsbooks this season.
• The Rays have won 41.3% of the games this season they were the underdog on the moneyline (31-44).
• When it has played as a moneyline underdog with odds of -102 or longer, Tampa Bay has gone 26-35 (42.6%).
• The Rays have played in 152 games with an over/under set, and have combined with their opponents to go over the total 67 times (67-77-8).
• The Rays have a 67-85-0 record against the spread this season (covering 44.1% of the time).

Orioles Player Leaders

• Gunnar Henderson has 153 hits and an OBP of .349 to go with a slugging percentage of .437. All three of those stats lead Baltimore hitters this season. He has a .274 batting average, as well.
• Among all qualified batters in the majors, he is 33rd in batting average, 39th in on-base percentage, and 68th in slugging.
• Jackson Holliday is hitting .245 with 21 doubles, three triples, 17 home runs and 54 walks. He's slugging .381 with an on-base percentage of .316.
• He ranks 100th in batting average, 99th in on-base percentage and 124th in slugging in the majors.
• Jordan Westburg is batting .264 with a .450 slugging percentage and 35 RBI this year.
• Adley Rutschman has been key for Baltimore with 70 hits, an OBP of .307 plus a slugging percentage of .369.

Rays Player Leaders

• Junior Caminero has totaled 151 hits, a team-best for the Rays. He's batting .259 and slugging .533 with an on-base percentage of .304.
• Including all the qualifying hitters in the big leagues, he ranks 65th in batting average, 117th in on-base percentage and eighth in slugging percentage.
• Yandy Diaz's .366 OBP and .485 slugging percentage both pace his team. He has a batting average of .301.
• Including all qualifying hitters, he ranks eighth in batting average, 14th in on-base percentage and 24th in slugging percentage.
• Brandon Lowe has 18 doubles, 30 home runs and 37 walks while hitting .257.
• Chandler Simpson has 14 doubles, three triples and 20 walks while batting .298.

Orioles vs Rays Head to Head

• 9/23/2025: 6-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/20/2025: 5-3 BAL (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/19/2025: 4-3 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/18/2025: 11-1 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/29/2025: 5-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/28/2025: 11-3 TB (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/27/2025: 22-8 BAL (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/19/2025: 4-1 BAL (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/18/2025: 12-8 TB (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/17/2025: 5-1 BAL (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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