Orioles vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 9

Odds updated as of 6:14 p.m.

MLB action on Tuesday includes the Baltimore Orioles playing the Pittsburgh Pirates.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Orioles vs Pirates Game Info

• Baltimore Orioles (66-77) vs. Pittsburgh Pirates (64-80)
• Date: Tuesday, September 9, 2025
• Time: 6:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and SportsNet PT

Orioles vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-154) | PIT: (+130)
• Spread: BAL: -1.5 (+136) | PIT: +1.5 (-164)
• Total: 8 -- Over: (-105) | Under: (-115)

Orioles vs Pirates Probable Starting Pitchers

Probable Pitchers: Kyle Bradish (Orioles) - 0-1, 3.60 ERA vs Mike Burrows (Pirates) - 2-4, 4.08 ERA

The probable pitchers are Kyle Bradish (0-1) for the Orioles and Mike Burrows (2-4) for the Pirates. Bradish has a record of 1-1-0 ATS in two starts with a spread this season. This will be Bradish's first game as the moneyline favorite this season. When Burrows starts, the Pirates are 8-7-0 against the spread. The Pirates have been the moneyline underdog in 12 of Burrows' starts this season, and they went 4-8 in those matchups.

Orioles vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Orioles win (58.1%)

Orioles vs Pirates Moneyline

• Looking at the moneyline for Orioles-Pirates, Baltimore is the favorite at -154, and Pittsburgh is +130 playing on the road.

Orioles vs Pirates Spread

• The Orioles are hosting the Pirates and are favored by 1.5 runs on the spread. The Orioles are +136 to cover the runline, with the Pirates being -164.

Orioles vs Pirates Over/Under

• A combined run total of 8 has been set for Orioles-Pirates on Sept. 9, with the over at -105 and the under at -115.

Bet on Baltimore Orioles vs. Pittsburgh Pirates on FanDuel today!

Orioles vs Pirates Betting Trends

• The Orioles have come away with 26 wins in the 57 contests they have been listed as the favorites in this season.
• Baltimore has a record of 4-5 in contests when sportsbooks favor them by -154 or more on the moneyline.
• The Orioles' games have gone over the total in 60 of their 140 opportunities.
• The Orioles are 68-72-0 against the spread in their 140 games with a line set by sportsbooks this season.
• The Pirates have won 42.7% of the games this season they were the moneyline underdog (41-55).
• Pittsburgh is 18-28 (winning just 39.1% of its games) when it has played as a moneyline underdog of +130 or longer.
• The Pirates have played in 136 games with a set over/under, and have combined with their opponents to go over the total 54 times (54-76-6).
• The Pirates have collected a 74-62-0 record against the spread this season (covering 54.4% of the time).

Orioles Player Leaders

• Gunnar Henderson has 139 hits and an OBP of .347 to go with a slugging percentage of .448. All three of those stats lead Baltimore hitters this season. He has a .274 batting average, as well.
• Among qualified hitters in the majors, his batting average ranks 34th, his on-base percentage ranks 43rd, and he is 59th in slugging.
• Jackson Holliday is batting .248 with 20 doubles, three triples, 17 home runs and 47 walks. He's slugging .394 with an on-base percentage of .316.
• His batting average is 94th among qualified players, his on-base percentage 101st, and his slugging percentage 112th.
• Ryan Mountcastle is batting .260 with a .374 slugging percentage and 30 RBI this year.
• Colton Cowser has been key for Baltimore with 57 hits, an OBP of .273 plus a slugging percentage of .396.

Pirates Player Leaders

• Bryan Reynolds has racked up a slugging percentage of .411 and has 130 hits, both team-high marks for the Pirates. He's batting .248 and with an on-base percentage of .316.
• He ranks 94th in batting average, 101st in on-base percentage and 89th in slugging percentage among all qualifying hitters in the majors.
• Oneil Cruz is hitting .201 with 17 doubles, two triples, 19 home runs and 60 walks. He's slugging .384 with an on-base percentage of .302.
• His batting average is 147th among all qualified players, his on-base percentage ranks 123rd, and he is 123rd in slugging.
• Andrew McCutchen has put up a team-high .339 on-base percentage.
• Tommy Pham is batting .261 with 17 doubles, a triple, eight home runs and 39 walks.

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