Orioles vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 11

Odds updated as of 9:11 p.m.

The Baltimore Orioles will face the Pittsburgh Pirates in MLB action on Thursday.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Orioles vs Pirates Game Info

• Baltimore Orioles (67-77) vs. Pittsburgh Pirates (64-81)
• Date: Thursday, September 11, 2025
• Time: 1:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and SportsNet PT

Orioles vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-142) | PIT: (+120)
• Spread: BAL: -1.5 (+134) | PIT: +1.5 (-162)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Orioles vs Pirates Probable Starting Pitchers

Probable Pitchers: Cade Povich (Orioles) - 3-7, 5.16 ERA vs Johan Oviedo (Pirates) - 2-0, 2.70 ERA

This contest's pitching matchup is set, as the Orioles will send Cade Povich (3-7) to the mound, while Johan Oviedo (2-0) will answer the bell for the Pirates. Povich's team is 5-12-0 against the spread in his starts this season. Povich's team is 2-6 this season when he starts and they are the moneyline favorite. The Pirates have gone 4-1-0 ATS in Oviedo's five starts with a set spread. The Pirates have been the underdog on the moneyline in five of Oviedo's starts this season, and they went 3-2 in those games.

Orioles vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Orioles win (53.6%)

Orioles vs Pirates Moneyline

• The Orioles vs Pirates moneyline has Baltimore as a -142 favorite, while Pittsburgh is a +120 underdog on the road.

Orioles vs Pirates Spread

• The Pirates are at the Orioles, and are +1.5 on the runline. The Pirates are +134 to cover the spread, and the Orioles are -162.

Orioles vs Pirates Over/Under

• An over/under of 8.5 has been set for Orioles-Pirates on Sept. 11, with the over being -122 and the under -100.

Bet on Baltimore Orioles vs. Pittsburgh Pirates on FanDuel today!

Orioles vs Pirates Betting Trends

• The Orioles have been chosen as favorites in 58 games this year and have walked away with the win 27 times (46.6%) in those games.
• Baltimore has a record of 10-8 in contests when bookmakers favor them by -142 or more on the moneyline.
• The Orioles and their opponents have gone over the total this season in 60 of their 141 opportunities.
• The Orioles have posted a record of 68-73-0 against the spread this season.
• The Pirates have put together a 41-56 record in games they were the underdog on the moneyline (winning 42.3% of those games).
• Pittsburgh is 23-40 (winning only 36.5% of its games) when it has played as a moneyline underdog of +120 or longer.
• In the 137 games bookmakers have set an over/under for the Pirates, they have combined with opponents to go over the total 54 times (54-77-6).
• The Pirates have a 75-62-0 record against the spread this season (covering 54.7% of the time).

Orioles Player Leaders

• Gunnar Henderson has 139 hits and an OBP of .346 to go with a slugging percentage of .444. All three of those stats are tops among Baltimore hitters this season. He has a .272 batting average, as well.
• Among qualified hitters in MLB, he is 37th in batting average, 44th in on-base percentage, and 66th in slugging.
• Jackson Holliday is hitting .250 with 20 doubles, three triples, 17 home runs and 48 walks. He's slugging .395 with an on-base percentage of .318.
• His batting average is 92nd among qualified players, his on-base percentage 96th, and his slugging percentage 110th.
• Holliday enters this matchup looking to extend his two-game hit streak. During his last five outings he is batting .368 with two home runs, four walks and two RBIs.
• Ryan Mountcastle has collected 76 base hits, an OBP of .297 and a slugging percentage of .372 this season.
• Colton Cowser has been key for Baltimore with 57 hits, an OBP of .272 plus a slugging percentage of .390.

Pirates Player Leaders

• Bryan Reynolds has totaled 130 hits with a .408 slugging percentage, both team-best stats for the Pirates. He's batting .246 and with an on-base percentage of .315.
• Including all qualified hitters, he is 96th in batting average, while his on-base percentage is 103rd and he is 93rd in slugging.
• Oneil Cruz has 17 doubles, two triples, 19 home runs and 61 walks while hitting .202. He's slugging .384 with an on-base percentage of .304.
• He is currently 146th in batting average, 121st in on-base percentage and 120th in slugging percentage among all qualifying batters.
• Andrew McCutchen a has .337 on-base percentage to lead the Pirates.
• Tommy Pham is batting .261 with 17 doubles, a triple, nine home runs and 40 walks.

Orioles vs Pirates Head to Head

• 9/9/2025: 3-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/7/2024: 3-2 PIT (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/6/2024: 5-4 PIT (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/5/2024: 5-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/14/2023: 4-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/13/2023: 2-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/12/2023: 6-3 BAL (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/7/2022: 8-1 PIT (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/6/2022: 6-3 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!