Oregon vs Oklahoma State Prediction, Odds, Picks, Best Bets for Week 2 2025

College football's Saturday slate includes the Oregon Ducks facing the Oklahoma State Cowboys.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

Oregon vs Oklahoma State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oregon: (-7143) | Oklahoma State: (+2000)
• Spread: Oregon: -28.5 (-104) | Oklahoma State: +28.5 (-118)
• Total: 55.5 -- Over: (-105) | Under: (-115)

Oregon vs Oklahoma State Betting Trends

• Oregon hasn won once against the spread this year.
• Oregon has covered every time (1-0) as a 28.5-point favorite or greater this season.
• Oregon and its opponent have not failed to hit the over in any game this season.
• Oklahoma State is winless against the spread this season.
• No Oklahoma State game has gone over the point total this year.

Oregon vs Oklahoma State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Ducks win (98.3%)

Oregon vs Oklahoma State Point Spread

Oklahoma State is an underdog by 28.5 points against Oregon. Oklahoma State is -118 to cover the spread, and Oregon is -104.

Oregon vs Oklahoma State Over/Under

Oregon versus Oklahoma State, on Sept. 6, has an over/under of 55.5, with the over being -105 and the under -115.

Oregon vs Oklahoma State Moneyline

Looking at the moneyline for Oklahoma State-Oregon, Oklahoma State is the underdog at +2000, and Oregon is -7143.

Oregon vs. Oklahoma State Points Insights

• The Ducks had an average implied point total of 35.2 last season, which is 6.8 points lower than their implied total in Saturday's game (42).
• The average implied point total last season for the Cowboys (34.8) is 20.8 more points than the team's implied total in this matchup (14).

Oregon vs. Oklahoma State Game Info

• Game day: Saturday, September 6, 2025
• Game time: 3:30 p.m. ET
• TV channel: CBS
• Location: Eugene, Oregon
• Stadium: Autzen Stadium

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Check out even more in-depth Oregon vs. Oklahoma State analysis on FanDuel Research.